Table 4 All-cause in-hospital mortality in groups based on predefined PaO₂/FiO₂ and PEEP cutoffs at hypoxemia onset and after 24 h

At onset

Group I, n = 216

Group II, n = 92

Group III, n = 223

Group IV, n = 158

P value for trend

Hospital mortality, n (%)

71 (32.9)

33 (35.9)

85 (38.1)

53 (33.5)

0.65

ICU mortality, n (%)

50 (23.1)

25 (27.2)

59 (26.5)

35 (22.2)

0.99

90-day mortality, n (%)

86 (39.8)

36 (39.1)

103 (46.2)

66 (41.8)

0.40

VFD28, days [IQR]

22 [5–25]

22 [0–24]

21 [0–25]

21 [3–25]

0.28^#

ICUFD28, days [IQR]

23 [19–25]

22 [18–24]

22 [18–25]

22 [17–24]

0.09^#

At 24 h

Group I, n = 296

Group II, n = 96

Group III, n = 177

Group IV, n = 120

P value for trend

Hospital mortality, n (%)

90 (30.4)

29 (30.2)

66 (37.3)

57 (47.5)

< 0.01

ICU mortality, n (%)

54 (18.2)

19 (19.8)

51 (28.8)

45 (37.5)

< 0.01

90-day mortality, n (%)

119 (40.2)

33 (34.4)

75 (42.4)

64 (53.3)

0.03

VFD28, days [IQR]

23 [14–25]

21 [4–24]

22 [0–25]

16 [0–23]

< 0.01^#

ICUFD28, days [IQR]

22 [19–25]

21 [15–25]

22 [19–25]

22 [15–25]

0.02^#