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Table 2 AP activity and markers of inflammation and lung injury in BALF, corrected for dilution factor

From: Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

Measure

Patients with ARDS (N = 25)

Patients not having ARDS (N = 58)

p value

AP (U/L)

0.33 (0.14–1.20)

0.55 (0.21–1.42)

0.369

IL-6 (pg/ml)

46.57 (7.62–130.77)

17.55 (4.35–52.29)

0.128

IL-8 (pg/ml)

274.48 (108.96–3047.86)

341.91 (126.69–1369.8)

0.666

IL-1β (pg/ml)

17.91 (0.64–55.44)

10.54 (2.03–71.70)

0.603

TNF-α (pg/ml)

1.05 (0.19–7.09)

1.55 (0.44–5.00)

0.732

MPO (ng/ml)

30.62 (7.48–127.56)

98.60 (27.22–266.61)

0.061

SP-D (ng/ml)

14.45 (5.20–94.34)

11.35 (3.89–36.46)

0.308

  1. Data is presented as median with IQR according to data distribution
  2. AP alkaline phosphatase, BALF bronchoalveolar lavage fluid, IL interleukin, MPO myeloperoxidase, SP-D surfactant protein D, TNF tumor necrosis factor