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Table 2 AP activity and markers of inflammation and lung injury in BALF, corrected for dilution factor

From: Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

Measure Patients with ARDS (N = 25) Patients not having ARDS (N = 58) p value
AP (U/L) 0.33 (0.14–1.20) 0.55 (0.21–1.42) 0.369
IL-6 (pg/ml) 46.57 (7.62–130.77) 17.55 (4.35–52.29) 0.128
IL-8 (pg/ml) 274.48 (108.96–3047.86) 341.91 (126.69–1369.8) 0.666
IL-1β (pg/ml) 17.91 (0.64–55.44) 10.54 (2.03–71.70) 0.603
TNF-α (pg/ml) 1.05 (0.19–7.09) 1.55 (0.44–5.00) 0.732
MPO (ng/ml) 30.62 (7.48–127.56) 98.60 (27.22–266.61) 0.061
SP-D (ng/ml) 14.45 (5.20–94.34) 11.35 (3.89–36.46) 0.308
  1. Data is presented as median with IQR according to data distribution
  2. AP alkaline phosphatase, BALF bronchoalveolar lavage fluid, IL interleukin, MPO myeloperoxidase, SP-D surfactant protein D, TNF tumor necrosis factor