Tertile 1 ((Post-LPS) - (Pre-LPS) <= -3.09 (n=66) | Tertile 2 ((Post-LPS) - (Pre-LPS) <= 19.42 (n=67) | Tertile 3 ((Post-LPS) - (Pre-LPS) > 19.42 (n=67) | Total cohort (n=200) | P-value | |
---|---|---|---|---|---|
Suspected nosocomial infection: N (%) | 34 (52%) | 35 (52%) | 39 (58%) | 108 (54%) | |
Total positive adjudicated infections: n | 21 | 16 | 29 | 66 | 0.489 |
Adjudicated positive infections per subject: Mean ± SD | 0.3 ± 0.7 | 0.2 ± 0.5 | 0.4 ± 0.8 | 0.3 ± 0.7 | 0.22 |
Source of positive infections | |||||
Surgical | 2 (9.5%) | 1 (6.3%) | 1 (3.4%) | 4 (2.0%) | |
Skin-soft tissue | 1 (4.8%) | 0 (0.0%) | 2 (6.9%) | 3 (1.5%) | |
Catheter BSI | 1 (4.8%) | 0 (0.0%) | 4 (13.8%) | 5 (2.5%) | |
Primary BSI | 3 (14.3%) | 0 (0.0%) | 3 (10.3%) | 6 (3.0%) | |
UTI | 2 (9.5%) | 2 (12.5%) | 6 (20.7%) | 10 (14.9%) | |
Intra-abdominal | 1 (4.8%) | 1 (6.3%) | 0 (0.0%) | 2 (1.0%) | |
Lower RTI | 2 (9.5%) | 6 (37.5%) | 2 (6.9%) | 10 (5.0%) | |
ICU Pneumonia | 9 (42.9%) | 4 (25.0%) | 10 (34.5%) | 23 (11.5%) | |
Other | 0 (0.0%) | 2 (12.5%) | 1 (3.4%) | 3 (1.5%) | |
ICU Mortality: n (%) | 24 (36.4%) | 20 (29.9%) | 21 (31.3%) | 65 (32.5%) | 0.703 |
Hospital mortality: n (%) | 25 (37.9%) | 21 (31.3%) | 24 (35.8%) | 70 (35.0%) | 0.721 |
90-day mortality: n (%) | 26 (39.4%) | 24 (35.8%) | 26 (38.8%) | 76 (38.0%) | 0.901 |
ICU length of stay | 0.743 | ||||
Median [IQR] | 9.1 [5.5 to 13.8] | 9.0 [6.9 to 13.3] | 9.0 [5.3 to 15.9] | 9.0 [5.9 to 15.2] | |
Hospital length of stay | 0.699 | ||||
Median [IQR] | 17.6 [7.7 to 30.3] | 14.6 [8.5 to 33.9] | 19.1 [9.0 to 34.0] | 16.8 [8.5 to 32.3] |