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Table 1 Baseline characteristics, and main outcome of patients receiving on-demand nebulizations vs. routine nebulizations

From: Effect of routine vs on-demand nebulization of acetylcysteine with salbutamol on accumulation of airway secretions in endotracheal tubes: substudy of a randomized clinical trial

Baseline characteristic

On-demand nebulization group

(n = 36)

Routine nebulization group

(n = 36)

Age, median (IQR), years

65 [59–73]

61 [51–69]

Women, no. (%)

11 (31)

12 (33)

BMI, median (IQR), kg/m2

25 [23 -29]

25 [23–28]

APACHE II, median (IQR)

20 [10—22]

17 [10–20]

Reason of ICU admission, no. (%)

 Medical

24 (67)

23(64)

 Surgical

12 (33)

13 (36)

Reason of invasive ventilation, no. (%)

 OHCA

5 (14)

4 (11)

 Postoperative ventilation

6 (17)

3 (8)

 Head trauma or brain surgery

7 (19)

4 (11)

 Pneumonia

3 (8)

1 (3)

 Sepsis

1 (3)

4 (11)

 Cardiac failure

1 (3)

4 (11)

 Trauma

4 (11)

8 (22)

 Aspiration

1 (3)

2 (6)

 ARDS

0 (0)

1 (3)

 Respiratory insufficiency

8(22)

5 (14)

Comorbidity, no, (%)

 Diabetes mellitus

9 (25)

4 (11)

 Cardio-vascular disease

7 (19)

8 (22)

 Pulmonary disease

3 (8)

3 (8)

 Immunosuppression

8 (22)

3 (8)

Outcome data

 Exposure of ETT to invasive ventilation, median (IQR), days*

6 [2]

5 [2–14]

  1. IQR, interquartile range; BMI, body mass index; APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; OHCA, out of hospital cardiac arrest; ETT, endotracheal tube