Baseline characteristic | On-demand nebulization group (n = 36) | Routine nebulization group (n = 36) |
---|---|---|
Age, median (IQR), years | 65 [59–73] | 61 [51–69] |
Women, no. (%) | 11 (31) | 12 (33) |
BMI, median (IQR), kg/m2 | 25 [23 -29] | 25 [23–28] |
APACHE II, median (IQR) | 20 [10—22] | 17 [10–20] |
Reason of ICU admission, no. (%) | ||
Medical | 24 (67) | 23(64) |
Surgical | 12 (33) | 13 (36) |
Reason of invasive ventilation, no. (%) | ||
OHCA | 5 (14) | 4 (11) |
Postoperative ventilation | 6 (17) | 3 (8) |
Head trauma or brain surgery | 7 (19) | 4 (11) |
Pneumonia | 3 (8) | 1 (3) |
Sepsis | 1 (3) | 4 (11) |
Cardiac failure | 1 (3) | 4 (11) |
Trauma | 4 (11) | 8 (22) |
Aspiration | 1 (3) | 2 (6) |
ARDS | 0 (0) | 1 (3) |
Respiratory insufficiency | 8(22) | 5 (14) |
Comorbidity, no, (%) | ||
Diabetes mellitus | 9 (25) | 4 (11) |
Cardio-vascular disease | 7 (19) | 8 (22) |
Pulmonary disease | 3 (8) | 3 (8) |
Immunosuppression | 8 (22) | 3 (8) |
Outcome data | ||
Exposure of ETT to invasive ventilation, median (IQR), days* | 6 [2] | 5 [2–14] |