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Table 2 Arterial blood gas analysis, hemoglobin and systemic carbon dioxide and oxygen variables

From: Regional venous–arterial CO2 to arterial–venous O2 content difference ratio in experimental circulatory shock and hypoxia

Parameters

BL

3 h

6 h

12 h

18 h

End

pH

7.48 (7.41–7.53)

7.46 (7.31–7.52)

7.45 (7.29–7.54)

7.44 (7.25–7.58)

7.44 (7.32–7.56)

7.41 (7.18–7.59)

Bicarbonate (mmol/l)

27.2 (23.9–29.6)

26.3 (22.0–29.9)

26.2 (21.6–30.8)

26.6 (19.8–30.9)

26.9 (21.8–31.8)

26.9 (13.9–33.5)

Base excess (mmol/l)

3.9 (0.1–6.5)

2.8 (− 2.8 to 6.6)

2.8 (− 2.8 to 7.4)

3.0 (− 4.9 to 8.2)

3.2 (− 2.2 to 8.5)

2.6 (− 9.0 to 8.7)

PaCO2 (mm Hg)

37.7 (33.1–41.8)

38.0 (29.7–50.7)

38.6 (31.3–51.5)

39.3 (33.3–53.1)

38.6 (34.0–56.7)

41.1 (17.7–80.3)

PaO2 (mm Hg)

137 (81–177)

119 (49–214)

121 (43–172)

118 (34–183)

127 (38–203)

110 (44–218)

SpO2 (%)

97 (90–100)

96 (69–100)

96 (55–99)

96 (55–98)

96 (50–97)

95 (46–98)

Arterial hemoglobin (g/dl)

8.9 (6.3–11.2)

9.2 (7.0–13.8)

9.4 (6.4–14.2)

9.1 (6.6–13.5)

8.4 (6.6–13.7)

8.6 (5.2–13.0)

CaCO2 (ml/dl)

56.5 (49.5–61.4)

54.6 (44.5–62.4)

54.9 (44.7–63.5)

55.4 (43.5–64.0)

57.0 (45.4–66.4)

56.0 (28.4–73.5)

CvCO2 (ml/dl)

62.3 (47.2–67.2)

60.0 (51.4–68.3)

59.5 (51.4–69.2)

61.1 (52.0–67.9)

62.0 (52.5–69.4)

61.9 (43.9–75.1)

Cv-aCO2 (ml/dl)

5.7 (1.9–10.0)

5.5 (0.1–9.6)

5.4 (1.0–10.8)

5.5 (1.8–10.5)

5.5 (2.3–9.7)

5.1 (1.6–19.3)

Pv-aCO2 (mmHg)

8.4 (0.9–11.7)

8.4 (3.1–15.1)

7.8 (1.7–14.2)

8.9 (2.9–16.7)

8.5 (0.5–18.6)

9.4 (4.6–64.4)

CaO2 (ml/dl)

12.1 (8.7–14.9)

12.3 (8.2–17.5)

12.5 (7.0–18.4)

11.8 (6.6–18.3)

11.2 (5.3–18.2)

10.7 (5.3–17.1)

CvO2 (ml/dl)

6.3 (2.9–8.9)

6.9 (2.1–11.6)

7.1 (1.0–13.5)

6.7 (2.7–11.0)

6.8 (1.5–11.2)

6.1 (0.8–12.8)

Ca-vO2 (ml/l)

5.6 (4.2–8.1)

5.7 (3.5–8.1)

5.2 (2.8–9.2)

5.2 (2.6–9.0)

4.4 (3.0–9.6)

4.6 (2.9–11.8)

Cv-aCO2/Ca-vO2

1.0 (0.4–1.7)

1.0 (0.0–1.6)

1.0 (0.3–1.8)

1.0 (0.5–1.6)

1.1 (0.5–2.0)

1.0 (0.3–3.8)

Pv-aCO2/Ca-vO2 (mmHg ml O2/dl)

1.5 (0.1–2.2)

1.5 (0.8–2.8)

1.5 (0.4–2.1)

1.7 (1.0–2.6)

1.9 (0.1–2.5)

2.0 (1.1–6.2)

  1. Values represent median and range. BL = baseline, End = end of experiment after 24 h of randomization or before death if earlier. PaO2 = arterial oxygen partial pressure, PaCO2 = arterial carbon dioxide partial pressure, SpO2 = peripheral oxygen saturation, CaCO2 = arterial CO2 content, CvCO2 = venous CO2 content, Cv-aCO2 = venous–arterial CO2 content difference, Pv-aCO2 = venous-to-arterial carbon dioxide difference, CaO2 = arterial O2 content, CvO2 = venous O2 content, Ca-vO2 = arterial–venous O2 content difference, Cv-aCO2/Ca-vO2 = venous–arterial CO2 to arterial–venous O2 content difference ratio, Pv-aCO2/Ca-vO2 = ratio between venous-to-arterial carbon dioxide difference and arterial–venous oxygen content difference