TY - JOUR AU - Martinez-Gonzalez, Enrique AU - Garcia-Olmo, Dolores AU - Mayordomo-Aranda, Empar AU - Granada-Picazo, Maria AU - Gomez-Juarez, Monica AU - Moreno-Cuesta, Jeronimo PY - 2020 DA - 2020/11/18 TI - Does hemofiltration protect the brain after head trauma? An experimental study in rabbits JO - Intensive Care Medicine Experimental SP - 66 VL - 8 IS - 1 AB - Traumatic brain injury (TBI) is one of the most frequent and severe neurological diseases. In the last few decades, significant advances have been made in TBI pathophysiology and monitoring, however new treatments have not emerged. Although the central nervous system (CNS) has been historically defined as an immunologically privileged organ, recent studies show the increasingly predominant role of inflammatory and apoptotic phenomena in the pathogenesis of TBI. Inflammatory response mediators can be eliminated with continuous renal replacement therapies (CRRT). Our aim was to investigate whether hemofiltration protects the brain after head trauma in an experimental study in animals. SN - 2197-425X UR - https://doi.org/10.1186/s40635-020-00357-5 DO - 10.1186/s40635-020-00357-5 ID - Martinez-Gonzalez2020 ER -