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Table 1 Baseline animal characteristics, ischemic times and perfusate composition

From: Flow-controlled ventilation during EVLP improves oxygenation and preserves alveolar recruitment

Baseline animal characteristics VCV (n = 7)
Median (25–75% IQR)
FCV (n = 7)
Median (25–75% IQR)
p value
Pig weight (kg) 38.8 (36.3–39.6) 39.6 (36.0–41.4) 0.40
Lung compliance donor (mL/cm H2O) 34 (32–36) 36 (28–38) 0.99
PaO2/FiO2 ratio at 100 FiO2 (mmHg) 529 (469–552) 546 (523–581) 0.21
Respiratory rate (breaths/min) 22 (20–22) 20 (20–22) 0.59
MAP (mmHg) 110 (99–112) 106 (90–107) 0.43
Heart rate (bpm) 108 (89–116) 84 (72–106) 0.32
Hb (mg/dL) 10.9 (10.6–11.1) 10.4 (10.2–10.5) 0.09
WBC count (109/L) 14.6 (13.2–17.2) 14.8 (11.1–16.4) 0.62
Neutrophils (%) 40 (31–41) 31 (27–33) 0.18
Ischemic time
 Warm ischemic time (min) 120 (120–120) 120 (116–120) 0.27
 Cold ischemic time (min) 44 (43–48) 48 (47–50) 0.13
Perfusate composition
 Glucosis (mg/dL) 234 (230–239) 229 (222–234) 0.18
 HCO3 (mmol/L) 32.5 (31.2–34.8) 32.5 (31.5–32.8) 0.98
 K+ (mmol/L) 3.5 (3.5–3.6) 3.5 (3.5–3.6) 0.88
 Na2+ (mmol/L) 158 (158–159) 156 (155–158) 0.09
 Cl (mmol/L) 106 (105–107) 105 (104–107) 0.71
 Ca2+ (mmol/L) 0.51 (0.49–0.54) 0.48 (0.42–0.51) 0.10
 Osmolality (mmol/kg H2O) 318 (317–321) 319 (314–320) 0.92
 Albumin (g/L) 72 (69–75) 71 (70–73)  > 0.99
  1. Baseline animal characteristics, ischemic times and perfusate composition did not differ between VCV and FCV
  2. VCV volume-controlled ventilation, FCV flow-controlled ventilation, IQR interquartile range, kg kilogram, mL milliliters, PaO2 partial pressure of oxygen, FiO2 fraction of inspiratory oxygen, cm centimeter, bpm beats per minute, Hb hemoglobin, mg milligram, dL deciliter, WBC white blood cell, min minutes, mmol millimole, L liters, g grams