Table 1 Baseline animal characteristics, ischemic times and perfusate composition
From: Flow-controlled ventilation during EVLP improves oxygenation and preserves alveolar recruitment
Baseline animal characteristics | VCV (n = 7) Median (25–75% IQR) | FCV (n = 7) Median (25–75% IQR) | p value |
|---|---|---|---|
Pig weight (kg) | 38.8 (36.3–39.6) | 39.6 (36.0–41.4) | 0.40 |
Lung compliance donor (mL/cm H2O) | 34 (32–36) | 36 (28–38) | 0.99 |
PaO2/FiO2 ratio at 100 FiO2 (mmHg) | 529 (469–552) | 546 (523–581) | 0.21 |
Respiratory rate (breaths/min) | 22 (20–22) | 20 (20–22) | 0.59 |
MAP (mmHg) | 110 (99–112) | 106 (90–107) | 0.43 |
Heart rate (bpm) | 108 (89–116) | 84 (72–106) | 0.32 |
Hb (mg/dL) | 10.9 (10.6–11.1) | 10.4 (10.2–10.5) | 0.09 |
WBC count (109/L) | 14.6 (13.2–17.2) | 14.8 (11.1–16.4) | 0.62 |
Neutrophils (%) | 40 (31–41) | 31 (27–33) | 0.18 |
Ischemic time | |||
Warm ischemic time (min) | 120 (120–120) | 120 (116–120) | 0.27 |
Cold ischemic time (min) | 44 (43–48) | 48 (47–50) | 0.13 |
Perfusate composition | |||
Glucosis (mg/dL) | 234 (230–239) | 229 (222–234) | 0.18 |
HCO3− (mmol/L) | 32.5 (31.2–34.8) | 32.5 (31.5–32.8) | 0.98 |
K+ (mmol/L) | 3.5 (3.5–3.6) | 3.5 (3.5–3.6) | 0.88 |
Na2+ (mmol/L) | 158 (158–159) | 156 (155–158) | 0.09 |
Cl− (mmol/L) | 106 (105–107) | 105 (104–107) | 0.71 |
Ca2+ (mmol/L) | 0.51 (0.49–0.54) | 0.48 (0.42–0.51) | 0.10 |
Osmolality (mmol/kg H2O) | 318 (317–321) | 319 (314–320) | 0.92 |
Albumin (g/L) | 72 (69–75) | 71 (70–73) | > 0.99 |