Table 2 Comparison of inspiration synchronized vs continuous nebulizer with different GF:IF and nebulizer placements
Nebulizer placement | Nebulizer type | Inhaled dose (%) | p | |
|---|---|---|---|---|
GF:IF > 0.5 (n = 60) | GF:IF < 0.5 (n = 60) | |||
Inlet of humidifier | Continuous | 9.9 (8.2, 16.4) | 18.1 (16.7, 19.6) | < 0.001 |
Inspiration synchronized | 3.5 (2.2, 9.3) | 23.9 (20.6, 28.3) | < 0.001 | |
p | 0.001 | < 0.001 | ||
Close to patient | Continuous | 4.0 (3.6, 9.0) | 17.6 (15.2, 20.1) | < 0.001 |
Inspiration synchronized | 8.0 (6.8, 12.4) | 23.1 (13.4, 24.1) | < 0.001 | |
p | 0.010 | 0.604 | ||
Comparison of inspiration synchronized nebulizer placed at inlet of humidifier vs close to patient | 0.015 | 0.067 | ||
Comparison of inspiration synchronized and continuous nebulizer at its best position | 0.31 | < 0.001 | ||