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Intensive Care Medicine Experimental
Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: A novel experimental porcine model to assess the impact of differential pulmonary blood flow on ischemia–reperfusion injury after unilateral lung transplantation

Fig. 3

Histology. a The W/D ratios were assessed of lung biopsies at the end after 6 h reperfusion. No significant difference was observed between the low- vs. high-flow group in the right native lug (p = 0.49) and the left transplanted lung (p < 0.99). Data were analyzed with Mann–Whitney test; W/D, wet-to-dry weight ratio; RLL, right lower lobe; LLL, left lower lobe. Left (b) The native right lower lobe (RLL) of the low-flow (LF) group shows mild capillary congestion and mild septal neutrophilic infiltration without presence of intra-alveolar neutrophils. Right (c) The transplanted left lower lobe (LLL) of the low-flow (LF) group shows mild capillary congestion, presence of septal neutrophilic infiltration, intra-alveolar edema and intra-alveolar neutrophils. Left (d) The native right lower lobe (RLL) of the high-flow (HF) group shows prominent capillary congestion and presence of neutrophilic infiltration in the septa. Right (e) The transplanted left lower lobe (LLL) of the (HF) group shows presence of capillary congestion, prominent intra-alveolar edema and presence of septal and intra-alveolar neutrophilic infiltration

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