Effect of positive end-expiratory pressure on additional passive ventilation generated by CPR compressions in a porcine model

Intensive Care Medicine Experimental

Table 2 Pairwise comparisons of outcomes between positive end-expiratory levels

Pairs of PEEP levels	MVexp_L/min		VCO₂ L/min		PaCO₂ mmHg
Pairs of PEEP levels	Mean diff (SE)	^$P value	Mean diff (SE)	^$P value	Mean diff (SE)	^$P value
0, 5	− 0.33 (0.05)	< .0001	− 14.11 (1.12)	< .0001	3.33 (3.67)	0.367
0, 10	− 0.82 (0.05)	< .0001	− 16.7 (1.14)	< .0001	7.59 (3.67)	0.043
0, 15	− 0.88 (0.05)	< .0001	− 24.93 (1.09)	< .0001	9.11 (3.67)	0.016
0, 20	− 1 (0.05)	< .0001	− 21 (1.12)	< .0001	11.35 (3.67)	0.003
5, 10	− 0.49 (0.05)	< .0001	− 2.6 (1.16)	0.1656	4.26 (3.67)	0.250
5, 15	− 0.55 (0.05)	< .0001	− 10.83 (1.11)	< .0001	5.78 (3.67)	0.120
5, 20	− 0.67 (0.05)	< .0001	− 6.89 (1.14)	< .0001	8.02 (3.67)	0.033
10, 15	− 0.06 (0.05)	0.7795	− 8.23 (1.13)	< .0001	1.52 (3.67)	0.681
10, 20	− 0.18 (0.05)	0.0042	− 4.29 (1.16)	0.002	3.75 (3.67)	0.310
15, 20	− 0.12 (0.05)	0.0957	3.94 (1.11)	0.0037	2.24 (3.67)	0.544

MVexp expired minute ventilation, PaCO₂ partial pressure of carbon dioxide, PEEP positive end-expiratory pressure, VCO₂ volumetric capnography
^$P value used to compare the mean difference between the corresponding pairs of PEEP levels. Tukey’s method was used to adjust the level of significance for multiple comparisons