Variables | ICU | P | Hospital | P | Six months | P | |||
---|---|---|---|---|---|---|---|---|---|
Survivors n = 43 | Non-survivors n = 32 | Survivors n = 32 | Non-survivors n = 43 | Survivors n = 25 | Non-survivors n = 50 | ||||
Age | 64.14 (18.1) | 67.16 (14.7) | 0.443 | 61.97 (16.5) | 68.00 (16.6) | 0.122 | 62.1 (14.0) | 67.1 (17.8) | 0.228 |
Clinical admission at ICU | 25 (58%) | 21 (66%) | 0.51 | 21 (66%) | 25 (58%) | 0.51 | 16 (64%) | 30 (60%) | 0.737 |
Sex (male) | 26 (60%) | 16 (50%) | 0.366 | 18 (57%) | 24 (56%) | 0.97 | 15 (60%) | 27 (54%) | 0.622 |
Pulmonary sepsis | 21 (51%) | 12 (38%) | 0.24 | 18 (56%) | 16 (37%) | 0.101 | 13 (52%) | 21 (42%) | 0.412 |
Solid neoplasia | 13 (30%) | 4 (11%) | 0.07 | 9 (28%) | 8 (18%) | 0.33 | 6 (24%) | 11 (22%) | 0.845 |
Hematological neoplasia | 2 (4.6%) | 3 (9.4%) | 0.417 | 1 (3.1%) | 4 (9.3%) | 0.386 | 0 (0%) | 5 (10%) | 0.162 |
Cirrhosis | 1 (2.3%) | 4 (13%) | 0.081 | 1 (3.1%) | 4 (9.3%) | 0.386 | 1 (4.0%) | 4 (8.0%) | 0.66 |
COPD | 7 (16%) | 4 (13%) | 0.647 | 5 (16%) | 6 (14%) | 0.84 | 3 (12.0%) | 8 (16%) | 0.742 |
CKD | 5 (12%) | 2 (6.2%) | 0.428 | 5 (16%) | 2 (4.6%) | 0.11 | 4 (16%) | 3 (6%) | 0.161 |
Chronic hypertension | 11 (26%) | 13 (41%) | 0.167 | 9 (28%) | 15 (35%) | 0.534 | 7 (28%) | 17 (34%) | 0.6 |
Diabetes | 11 (26%) | 10 (31%) | 0.589 | 10 (32%) | 11 (26%) | 0.589 | 9 (36%) | 12 (24%) | 0.275 |
SvO2 (%) | 68.01 (6.1) | 71.36 (11.6) | 0.215 | 67.71 (9.0) | 70.70 (11.1) | 0.266 | 68.18 (9.1) | 70.06 (10.9) | 0.504 |
Lactate D1 (mmol/L) | 1.4 (1.1–2.1) | 2.8 (2.0–4.0) | 0.002 | 1.4 (1.1–1.9 | 2.55 (1.7–3.6 | 0.015 | 1.4 (0.9–1.6) | 2.2 (1.6–3.5) | 0.041 |
SOFA D1 | 7.63 (3.0) | 1.0 (2.4) | < 0.0001 | 7.25 (2.55) | 9.67 (2.95) | < 0.0001 | 7.40 (2.6) | 9.26 (3.0) | 0.011 |
SOFA D3 | 3 (2–5) | 12.5 (7–19.5) | < 0.0001 | 3 (1.7–5) | 9 (4–16.5) | < 0.0001 | 3 (1–4) | 7.5 (3.25–15.5) | < 0.0001 |
ΔSOFA < 0 | 38 (88%) | 11 (34%) | < 0.0001 | 28 (88%) | 21 (49%) | < 0.0001 | 22 (88%) | 27 (54%) | 0.004 |
SAPS 3 | 73.98 (13.2) | 78.60 (12.1) | 0.1 | 72.16 (13.1) | 78.77 (12.0) | 0.026 | 70.68 (11.2) | 78.58 (12.9) | 0.011 |
CRP (mg/L) | 153 (69.7–216) | 220 (119–284) | 0.02 | 153 (69–223) | 196 (119–269) | 0.062 | 153(72.6–209) | 188 (98–258) | 0.076 |
CRT D1 (s) | 4 (2–4) | 5.5 (3–8) | 0.04 | 3.5 (2–4) | 4 (3–7) | 0.046 | 4 (3–4) | 4 (2.25–7) | 0.319 |
BCE D1 | 0.354 (0.1) | 0.243 (0.1) | < 0.0001 | 0.378 (0.1) | 0.254 (0.1) | < 0.0001 | 0.380 (0.1) | 0.270 (0.1) | < 0.0001 |
BCE D3 | 0.456 (0.18) | 0.210 (0.1) | < 0.0001 | 0.535 (0.1) | 0.215 (0.1) | < 0.0001 | 0.543 (0.1) | 0.267 (0.2) | < 0.0001 |
ΔBCE > 0 | 33 (77%) | 2 (6.3%) | < 0.0001 | 31 (97%) | 4 (9.3%) | < 0.0001 | 24 (96%) | 11 (22%) | < 0.0001 |