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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Complement factor D is linked to platelet activation in human and rodent sepsis

Fig. 2

Height of complement factor D level predicts disease severity. A Kaplan–Meier curve: cut-off values were estimated from 25th, 50th and 75th percentile. Complement factor D (CFD) levels above 75th percentile were associated with earlier and higher in-hospital mortality. B Complement factor D: highest mortality was associated with significant higher complement factor D level in non-survivors compared to survivor group. C Non-survivors with no antiplatelet drugs showed significantly higher CFD plasma level compared to patient who survived. Statistics: *statistical difference between indicated groups with p < 0.05. A Log-rank test. #Statistical significance (p < 0.05) between non-survivor and survivors by means of B Student’s t-test or C Wilcoxon–Mann–Whitney. In total 79 patients

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