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Intensive Care Medicine Experimental
Fig. 6 | Intensive Care Medicine Experimental

Fig. 6

From: Progranulin signaling in sepsis, community-acquired bacterial pneumonia and COVID-19: a comparative, observational study

Fig. 6

ROC curves for the differentiation between patients with SIRS and sepsis for procalcitonin (PCT, A), C-reactive protein (CRP, B) and interleukin-6 (IL-6, C) in comparison to progranulin. Patients with sepsis and septic shock were combined for this analysis. The curves for progranulin are printed in red and the respective lines of the compared reference marker are outlined in blue. Lines printed in lighter colors represent measurements in the exploratory cohort and dashed lines the corresponding measurements in the confirmatory (validation) sample. Dark lines show the summary values from both samples. See text for AUC values and statistical comparison and Additional file 1: Tables S8 and S9 for further details

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