Intensive Care Medicine Experimental

Table 2 Generalized estimating equations results for the cytokines response to ICP elevation

From: Inflammatory markers assessment in an animal model of intracranial hypertension: a randomized trial

Cytokine	ICP (each 1 mmHg)		Wald statistics	p-value
Cytokine	Coefficient	Standard error	Wald statistics	p-value
IL-1α	0,001	0,001	9,68	0,002
IL-1β	0,082	0,028	8,48	0,004
IL-1ra	2,180	0,650	11,18	0,001
IL-2	− 0,001	0,001	2,47	0,116
IL-4	− 0,005	0,003	3,34	0,068
IL-6	0,082	0,032	6,58	0,010
IL-8	0,690	0,270	6,43	0,011
IL-10	− 0,003	0,004	0,49	0,483
IL-12	0,032	0,010	10,63	0,001
IL-18	0,036	0,014	6,79	0,009
TNF- α	− 0,151	0,040	14,19	< 0,001

ICP intracranial pressure. One degree of freedom for each model

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