Do alterations in pulmonary vascular tone result in changes in central blood volumes? An experimental study

Intensive Care Medicine Experimental

Table 1 Hemodynamic changes in response to induced hypoxia and co-administration of inhaled PGI₂, as well as the reaction to solitary administration of inhaled PGI₂

Data are presented as median (interquartile range). PGI₂, Aerosolized prostacyclin; PaO₂, Arterial Partial Pressure of Oxygen; SaO₂, Arterial Oxygen Saturation; Vd _circ, Effective circulating blood volume; MAP, Mean Arterial Pressure; CVP, Central Venous Pressure; PAP, Pulmonary Artery Pressure; PCWP, Pulmonary Capillary Wedge Pressure (PCWP); CO_Transonic, SV_Transonic, Cardiac Output, Stroke Volume derived from Transonic Flow Probe; PBV, Pulmonary Blood Volume; ITBV, Intrathoracic Blood Volume; Pmsa, mean systolic pressure analogue; Pvr, driving pressure for venous return; E_H, cardiac performance; RVR, resistance to venous return
^*P < 0.05 vs baseline
^$P < 0.05 Hypoxia vs hypoxia + PGI₂