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Table 3 Concentrations of NGAL, LFABP and HFABP

From: Neutrophil gelatinase-associated lipocalin does not originate from the kidney during reperfusion in clinical renal transplantation

 

Preoperative venous blood

Renal arterial blood (ART)

Renal venous blood (VEN)

Transrenal gradient (VEN–ART)

P-value (ART VS VEN)§

NGAL (ng/ml)

ALL (N = 28)

71.4 (53.9–90.0)

64.9 (46.5–83.4)

62.3 (47.3–86.7)

0.5 (− 6.4–6.0)

0.585

NO-DGF (N = 22)

71.4 (50.7–94.1)

65.6 (44.5–85.3)

59.8 (44.0–88.1)

0.3 (− 4.5–5.3)

0.78

DGF (N = 6)

70.6 (56.9–81.6)

64.9 (60.8–69.7)

63.2 (56.9–90.3)

2.7 (− 8.3–22.4)

0.46

P-VALUE (DGF VS NO-DGF) §§

0.89

0.98

0.37

0.494

 

LFABP (ng/ml)

ALL (N = 26)

48.5 (39.0–64.0)

56.7 (47.7–74.8)

78.0 (57.1–116.3)

8.4 (1.7–30.0)*

0.005*

NO-DGF (N = 20)

43.5 (36.6–61.6)

56.3 (44.7–66.3)

73.5 (53.3–88.0)

8.4 (2.3–24.1)*

0.001*

DGF (N = 6)

56.0 (48.3–104.1)

77.5 (54.5–125.6)

103.3 (68.7–131.4)

16.7 (− 13.0–45.3)

0.345

P-VALUE (DGF VS NO-DGF) §§

0.11

0.22

0.083

0.836

 

HFABP (ng/ml)

ALL (N = 24)

22.2 (15.8–34.1)

24.6 (16.2–33.9)

28.3 (24.6–38.1)

3.7 (1.1–5.0)*

0.003*

NO-DGF (N = 21)

21.6 (15.7–28.5)

23.2 (15.5–30.2)

27.8 (24.5–35.3)

3.7 (1.5–5.2)*

0.0007*

DGF (N = 3)

36.4 (35.5–65.1)

34.0 (33.8–66.8)

38.4 (35.8–62.4)

− 0.3 (-6.7–2.1)

0.59

P-VALUE (DGF VS NO-DGF) §§

0.031*

0.041*

0.122

0.172

 
  1. Data are median (interquartile range) for concentrations. All p-values are shown; §ART vs. VEN—Wilcoxon signed-rank test; §§DGF vs. no-DGF Mann–Whitney U test; Transrenal gradient (ART subtracted from VEN). *for statistically significant results (p < 0.05); NGAL neutrophil gelatinase-associated lipocalin, LFABP liver-type fatty-acid binding protein, HFABP heart-type fatty-acid binding protein, ART concentration in graft arterial blood, VEN concentration in graft venous blood, DGF Delayed Graft Function