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Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: Hysteretic device characteristics indicate cardiac contractile state for guiding mechanical circulatory support device use

Fig. 5

Receiver operating characteristic curve analysis for diagnostic performance. Diagnostic performance for prediction of directional change in contractility was quantified using AUC of ROC curves. Each contractility measure was compared with contractility change as indicated by changes in dP/dtmax detected using changepoint detection. a In the acute animal models, use of invasive pressure–volume measurement catheters allowed measurement of ESPVR and PRSWi as benchmarks to compare with systolic area performance. Quantified by AUC, systolic area had comparable or superior diagnostic capability to indicate changes in contractility compared to dP/dtmax. b In patient data, systolic area was compared with AUC and yielded

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