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Table 1 General physiological haemodynamic and systemic parameters for baseline, hypoperfusion and post resuscitation periods

From: Effects of norepinephrine infusion on cerebral energy metabolism during experimental haemorrhagic shock

Interval Control NE Control vs. NE group p value
Baseline (− 60)–0 min    
 MAP (mmHg) 88 (78–98) 78 (72–95) 0.198
 HR (bpm) 56 (55–87) 87 (74–103) 0.016*
 PbtO2 (mmHg) 22 (8–70) 37 (30–40) 0.880
 PaO2 (kPa) 53 (49–57) 37 (36–40) 0.001*
 PaCO2 (kPa) 5.6 (5.4–6) 6.4 (5.9–6.7)  < 0.001*
 b-Hemoglobin (mM/L) 5.8 (5.6–6.3) 5 (4.8–5.3)  < 0.001*
 b-Glucose (mM/L) 4.1 (3.7–6) 5.8 (3.9–8.1) 0.180
 b-Lactate (mM/L) ABG 0.9 (0.5–1) 0.5 (0.4–0.9) 0.753
 b-pH ABG 7.45 (7.44–7.48) 7.46 (7.43–7.5) 0.951
 Diuresis (mL) 25 (0–72.5) 0 (0–50) 0.274
Hypoperfusion 0–90 min    
 MAP (mmHg) 41 (40–42) 80 (75–86)  < 0.001*
 HR (bpm) 108 (63–180) 98 (85–115) 0.625
 PbtO2 (mmHg) 8 (4–18) 28 (23–34) 0.160
 PaO2 (kPa) 52 (46.6–53.9) 38 (35–41) 0.019
 PaCO2 (kPa) 5.5 (5.2–6.3) 6.3 (6.1–6.7) 0.031*
 b-Hemoglobin (mM/L) 5.7 (5–6.1) 5.1 (4.8–5.6) 0.189
 b-Glucose (mM/L) MD 6 (3.8–7.0) 4.9 (4.2–7.0) 0.974
 b-Lactate (mM/L) ABG 8.2 (2.7–13.7) 1.1 (0.9–1.7) 0.001*
 b-pH ABG 7.39 (7.23–7.4) 7.46 (7.43–7.49) 0.013
 Diuresis (mL) 0 (0.35) 11.5 (0–47.5) 0.380
Post resuscitation 180–240 min    
 MAP (mmHg) 56 (47–79) 74 (69–80) 0.037
 HR (bpm) 89 (76–107) 90 (76–99) 0.858
 PbtO2 (mmHg) 7 (2–10) 29 (13–34) 0.021
 PaO2 (kPa) 51(49–54) 38 (37–42)  < 0.001*
 PaCO2 (kPa) 6.5 (5.3–6.8) 6 (5.7–6.5) 0.665
 b-Hemoglobin (mM/L) 6.5 (6–6.7) 4.6 (4.2–4.9)  < 0.001*
 b-Glucose (mM/L) 2.8 (0.7–3.2) 3.6 (2.9–4.3) 0.432
 b-Lactate (mM/L) ABG 3.9 (2–8.4) 0.5 (0.3–0.6) 0.003*
 b-pH ABG 7.32 (7.29–7.39) 7.47 (7.45–7.51)  < 0.001*
 Diuresis (mL) 0 (0–30) 0 (0–4) 0.676
  1. NE group n = 8, control group n = 4. Values are medians (interquartile range). Test statistics performed with mixed effect model
  2. *Statistical significant p value < 0.05