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Table 1 General physiological haemodynamic and systemic parameters for baseline, hypoperfusion and post resuscitation periods

From: Effects of norepinephrine infusion on cerebral energy metabolism during experimental haemorrhagic shock

Interval

Control

NE

Control vs. NE group p value

Baseline (− 60)–0 min

   

 MAP (mmHg)

88 (78–98)

78 (72–95)

0.198

 HR (bpm)

56 (55–87)

87 (74–103)

0.016*

 PbtO2 (mmHg)

22 (8–70)

37 (30–40)

0.880

 PaO2 (kPa)

53 (49–57)

37 (36–40)

0.001*

 PaCO2 (kPa)

5.6 (5.4–6)

6.4 (5.9–6.7)

 < 0.001*

 b-Hemoglobin (mM/L)

5.8 (5.6–6.3)

5 (4.8–5.3)

 < 0.001*

 b-Glucose (mM/L)

4.1 (3.7–6)

5.8 (3.9–8.1)

0.180

 b-Lactate (mM/L) ABG

0.9 (0.5–1)

0.5 (0.4–0.9)

0.753

 b-pH ABG

7.45 (7.44–7.48)

7.46 (7.43–7.5)

0.951

 Diuresis (mL)

25 (0–72.5)

0 (0–50)

0.274

Hypoperfusion 0–90 min

   

 MAP (mmHg)

41 (40–42)

80 (75–86)

 < 0.001*

 HR (bpm)

108 (63–180)

98 (85–115)

0.625

 PbtO2 (mmHg)

8 (4–18)

28 (23–34)

0.160

 PaO2 (kPa)

52 (46.6–53.9)

38 (35–41)

0.019

 PaCO2 (kPa)

5.5 (5.2–6.3)

6.3 (6.1–6.7)

0.031*

 b-Hemoglobin (mM/L)

5.7 (5–6.1)

5.1 (4.8–5.6)

0.189

 b-Glucose (mM/L) MD

6 (3.8–7.0)

4.9 (4.2–7.0)

0.974

 b-Lactate (mM/L) ABG

8.2 (2.7–13.7)

1.1 (0.9–1.7)

0.001*

 b-pH ABG

7.39 (7.23–7.4)

7.46 (7.43–7.49)

0.013

 Diuresis (mL)

0 (0.35)

11.5 (0–47.5)

0.380

Post resuscitation 180–240 min

   

 MAP (mmHg)

56 (47–79)

74 (69–80)

0.037

 HR (bpm)

89 (76–107)

90 (76–99)

0.858

 PbtO2 (mmHg)

7 (2–10)

29 (13–34)

0.021

 PaO2 (kPa)

51(49–54)

38 (37–42)

 < 0.001*

 PaCO2 (kPa)

6.5 (5.3–6.8)

6 (5.7–6.5)

0.665

 b-Hemoglobin (mM/L)

6.5 (6–6.7)

4.6 (4.2–4.9)

 < 0.001*

 b-Glucose (mM/L)

2.8 (0.7–3.2)

3.6 (2.9–4.3)

0.432

 b-Lactate (mM/L) ABG

3.9 (2–8.4)

0.5 (0.3–0.6)

0.003*

 b-pH ABG

7.32 (7.29–7.39)

7.47 (7.45–7.51)

 < 0.001*

 Diuresis (mL)

0 (0–30)

0 (0–4)

0.676

  1. NE group n = 8, control group n = 4. Values are medians (interquartile range). Test statistics performed with mixed effect model
  2. *Statistical significant p value < 0.05