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Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Towards a biological definition of ARDS: are treatable traits the solution?

Fig. 1

There are many ways to parse ARDS into subgroups. Different ways to parse the ARDS population into subgroups some of which are subphenotypes. One patient can, therefore, belong to many different subgroups simultaneously, each of which could be a treatable trait. Top row from left to right: unselected ARDS; Berlin severity with mild, moderate and severe ARDS based on PaO2/FiO2 (light to dark blue); pulmonary (dark blue) and non-pulmonary (light orange) causes for ARDS; Focal (green) and non-Focal (yellow) ARDS based on chest CT. Bottom row from left to right: patients with (red) and without (yellow) apparent endothelial dysfunction; with (dark blue) and without (light blue) apparent epithelial injury; hyperinflammatory (orange) and hypoinflammatory systemic host response; hyperinflammatory (dark purple) and hypoinflammatory (light purple) alveolar host response

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