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Intensive Care Medicine Experimental
Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock

Fig. 5

Utility of non-invasive measures to estimate organ-specific outcomes. A Concurrent recovery of PtO2 and StO2 in brain. B Liver PtO2 recovered (> 75% baseline) before other tissues and muscle StO2. C Arterial lactate was associated with brain and kidney lactate but delayed liver and muscle lactate clearance (< 4 mM; baseline mean + SD). D Arterial lactate was associated with recovery in organ-specific lactate/pyruvate ratios (< 30). E Sublingual capillary flow (proportion perfused vessels; PPV) recovered similarly between treatment groups; (F) and an increase in sublingual capillary flow indicated that organ-specific capillary flow had improved (> 75% baseline). Data shown as mean or geometric mean according to normality test, with 95% confidence intervals. Mixed model ANOVA with Tukey correction for multiple comparisons; *p < 0.05, **p < 0.01, ***p < 0.001, ****p, 0.0001

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