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Intensive Care Medicine Experimental

Table 1 Hemodynamics

From: Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model

 

Baseline

1st hour

2nd hour

3rd hour

4th hour

5th hour

6th hour

ANOVA

(p value)

Edema group

MAP (mmHg)

82 ± 5

85 ± 10

68 ± 11

71 ± 10

82 ± 12

86 ± 13

81 ± 14

0.76

SAP (mmHg)

97 ± 10

103 ± 11

90 ± 8

92 ± 7

101 ± 8

107 ± 10

103 ± 10

0.35

DAP (mmHg)

62 ± 7

69 ± 8

52 ± 10

57 ± 12

67 ± 14

72 ± 15

66 ± 16

0.97

PAPmean (mmHg)

19 ± 3

30 ± 6

31 ± 2

39 ± 5

40 ± 3

38 ± 3

37 ± 5

0.59

PAOP (mmHg)

11 ± 2

13 ± 2

16 ± 4

14 ± 3

14 ± 1

15 ± 1

16 ± 1

0.78

CVP (mmHg)

8 ± 2

9 ± 2

11 ± 2

11 ± 1

11 ± 1

12 ± 1*

14 ± 3*

0.08

IAP (mmHg)

11 ± 2

11 ± 2

14 ± 4

14 ± 3

15 ± 3

14 ± 3

15 ± 4*

0.28

APP (mmHg)

72 ± 6

75 ± 9

58 ± 4

57 ± 11

68 ± 13

76 ± 6

66 ± 20

0.89

Cardiac rate (bpm)

83 ± 6

83 ± 15

101 ± 32

109 ± 23

108 ± 24

96 ± 18

93 ± 11*

0.16

Cardiac output (L/min)

2.7 ± 0.4

2.6 ± 0.5

2.5 ± 0.5

2.7 ± 1.4

2.4 ± 1.5

1.7 ± 0.3

2.1 ± 0.8

0.41

Control group

MAP (mmHg)

78 ± 15

82 ± 9

69 ± 5

75 ± 3

81 ± 11

84 ± 11

79 ± 11

0.76

SAP (mmHg)

96 ± 13

101 ± 8

88 ± 6

93 ± 4

97 ± 8

101 ± 9

100 ± 13

0.35

DAP (mmHg)

64 ± 16

66 ± 9

54 ± 5

62 ± 3

68 ± 12

70 ± 12

65 ± 15

0.97

PAPmean (mmHg)

19 ± 1

31 ± 5

32 ± 6

36 ± 10

38 ± 11

36 ± 9

3 ± 9

0.59

PAOP (mmHg)

12 ± 2

13 ± 2

15 ± 2

16 ± 2

16 ± 2

16 ± 2

16 ± 2

0.78

CVP (mmHg)

8 ± 1

9 ± 2

10 ± 2

10 ± 2

11 ± 2

11 ± 1

11 ± 2

0.08

IAP (mmHg)

10 ± 3

11 ± 3

13 ± 4

13 ± 3

13 ± 5

12 ± 3

11 ± 3

0.28

APP (mmHg)

68 ± 15

71 ± 8

57 ± 6

62 ± 3

68 ± 10

72 ± 9

68 ± 12

0.89

Cardiac rate (bpm)

84 ± 12

92 ± 9

106 ± 16

124 ± 19

116 ± 18

116 ± 14

118 ± 14

0.16

Cardiac output (L/min)

2.4 ± 0.3

2.6 ± 0.4

2.3 ± 0.4

2.1 ± 0.4

1.9 ± 0.5

2.0 ± 0.5

2.0 ± 0

5

0.41

  1. Hemodynamic parameters measured at the baseline and every hour during experiments in the two groups. Data are reported as mean; standard deviation. Statistically significant difference (p < 0.05) between the two groups found with multiple t-tests is reported as a * near to the Intervention Group values
  2. ANOVA analysis p values are reported in the dedicated columns next to the Edema group measurements
  3. MAP mean arterial pressure, SAP systolic arterial pressure, DAP diastolic arterial pressure, PAPmean pulmonary artery pressure (mean value), PAOP pulmonary artery occlusion pressure, CVP central venous pressure, IAP intra-abdominal pressure, APP abdominal perfusion pressure, mmHg millimeter mercury, bpm beat per minute, L/min liters per minute.
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