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Table 2 Respiratory and blood gas analysis parameters

From: Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model

 

Baseline

1st hour

2nd hour

3rd hour

4th hour

5th hour

6th hour

ANOVA

(p value)

Edema group

Airway pressure (peak)

12.0 ± 3.2

15.3 ± 3.4

20.8 ± 4.8

21.8 ± 4

21.8 ± 3.8*

22.2 ± 3.9

23 ± 4.9

0.10

Airway pressure (mean)

10.2 ± 4.9

13.7 ± 8.7

18.2 ± 8.6

18.5 ± 8.5

18.5 ± 8.5

18.7 ± 8.3

18.8 ± 8.1

0.82

EtCO2 (mmHg)

36.2 ± 2.7

37.9 ± 2.6

41.1 ± 3.4

42.3 ± 2.6

40.4 ± 3.4

39.4 ± 4.9

38.1 ± 5.9

0.66

pH

7.5 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

0.87

pO2 (kPa)

35.1 ± 2*

31.6 ± 8.1

33.5 ± 5.5

34.6 ± 11.6

33.7 ± 9.5

29.1 ± 4.8

27.2 ± 8.9

0.16

pCO2 (kPa)

5.3 ± 0.4

5.7 ± 0.4

6.2 ± 0.5

6.2 ± 0.2

6.0 ± 0.2

6.0 ± 0.2

6.2 ± 0.4

0.56

Lactate (mmol/L)

1.8 ± 0.6

2.1 ± 0.5

2.5 ± 0.5

3.2 ± 1.3

3.4 ± 1.6

3.3 ± 1.6

2.6 ± 1.4

0.04

Hb (gr/dL)

79.0 ± 7.0

84.0 ± 7.0

84.0 ± 4.0

86.0 ± 6.0

89.0 ± 7.0

89.0 ± 9.0

85.0 ± 10.0

0.12

SpO2 (%) venous

59.3 ± 3.6

60.1 ± 7.7

55.2 ± 11.2

51.9 ± 14.7

48.5 ± 16.6

44.2 ± 15.1

44.5 ± 9.0

0.21

Control group

Airway pressure (peak)

14.4 ± 3.0

17.0 ± 5.0

25.0 ± 9.0

27.0 ± 4.8

26.9 ± 4.1

26.9 ± 4.8

26.6 ± 4.6

0.10

Airway pressure (mean)

9.0 ± 3.6

9.9 ± 4.2

17.3 ± 5.6

18.4 ± 5.2

18.7 ± 5.3

18.7 ± 4.8

18.9 ± 5.1

0.82

EtCO2 (mmHg)

35.4 ± 2.7

37.2 ± 3.0

40.1 ± 4.5

41.5 ± 4.3

40.6 ± 4.3

43.9 ± 4.2

42 ± 4.1

0.66

pH

7.5 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.4 ± 0.1

7.3 ± 0.1

7.3 ± 0.1

0.87

pO2 (kPa)

24.4 ± 7.6

28.5 ± 5.4

32.1 ± 5.0

29.9 ± 8.6

29.5 ± 7.7

27.1 ± 7.0

28.4 ± 7.0

0.16

pCO2 (kPa)

5.1 ± 0.4

5.5 ± 0.7

5.8 ± 0.7

6.0 ± 0.5

5.9 ± 0.5

6.2 ± 0.7

6.4 ± 0.7

0.56

Lactate (mmol/L)

1.5 ± 0.4

1.9 ± 0.4

2.0 ± 0.4

2.2 ± 0.6

2.2 ± 0.6

2.1 ± 0.7

1.8 ± 0.5

0.04

Hb (g/dL)

81.0 ± 14.0

91.0 ± 12.0

93.0 ± 11.0

94.0 ± 8.0

94.0 ± 9.0

97.0 ± 11.0

94.0 ± 11.0

0.12

SpO2 (%) venous

50.7 ± 11.0

60.1 ± 5.1

51.7 ± 3.6

45.3 ± 6.2

38.3 ± 7.4

38.1 ± 6.0

39.3 ± 5.7

0.21

  1. Respiratory and blood gas analysis parameters measured at the baseline and every hour during experiments in the two groups. Data are reported as mean ± standard deviation
  2. Airways pressure (peak and mean) is reported in cmH2O
  3. Statistically significant difference (p < 0.05) found with multiple comparison between the two groups are reported as a * near the Intervention Group values
  4. ANOVA analysis p values are reported in the dedicated columns next to the Edema group measurements (p values < 0.05 are reported in bold)
  5. pO2 partial pressure of oxygen in arterial blood, pCO2 partial pressure of carbon dioxide in arterial blood, Hb hemoglobin, spO2 oxygen saturated hemoglobin in ven ous blood (jugular vein).