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Table 2 Respiratory and blood gas analysis parameters

From: Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model

  Baseline 1st hour 2nd hour 3rd hour 4th hour 5th hour 6th hour ANOVA
(p value)
Edema group
Airway pressure (peak) 12.0 ± 3.2 15.3 ± 3.4 20.8 ± 4.8 21.8 ± 4 21.8 ± 3.8* 22.2 ± 3.9 23 ± 4.9 0.10
Airway pressure (mean) 10.2 ± 4.9 13.7 ± 8.7 18.2 ± 8.6 18.5 ± 8.5 18.5 ± 8.5 18.7 ± 8.3 18.8 ± 8.1 0.82
EtCO2 (mmHg) 36.2 ± 2.7 37.9 ± 2.6 41.1 ± 3.4 42.3 ± 2.6 40.4 ± 3.4 39.4 ± 4.9 38.1 ± 5.9 0.66
pH 7.5 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 0.87
pO2 (kPa) 35.1 ± 2* 31.6 ± 8.1 33.5 ± 5.5 34.6 ± 11.6 33.7 ± 9.5 29.1 ± 4.8 27.2 ± 8.9 0.16
pCO2 (kPa) 5.3 ± 0.4 5.7 ± 0.4 6.2 ± 0.5 6.2 ± 0.2 6.0 ± 0.2 6.0 ± 0.2 6.2 ± 0.4 0.56
Lactate (mmol/L) 1.8 ± 0.6 2.1 ± 0.5 2.5 ± 0.5 3.2 ± 1.3 3.4 ± 1.6 3.3 ± 1.6 2.6 ± 1.4 0.04
Hb (gr/dL) 79.0 ± 7.0 84.0 ± 7.0 84.0 ± 4.0 86.0 ± 6.0 89.0 ± 7.0 89.0 ± 9.0 85.0 ± 10.0 0.12
SpO2 (%) venous 59.3 ± 3.6 60.1 ± 7.7 55.2 ± 11.2 51.9 ± 14.7 48.5 ± 16.6 44.2 ± 15.1 44.5 ± 9.0 0.21
Control group
Airway pressure (peak) 14.4 ± 3.0 17.0 ± 5.0 25.0 ± 9.0 27.0 ± 4.8 26.9 ± 4.1 26.9 ± 4.8 26.6 ± 4.6 0.10
Airway pressure (mean) 9.0 ± 3.6 9.9 ± 4.2 17.3 ± 5.6 18.4 ± 5.2 18.7 ± 5.3 18.7 ± 4.8 18.9 ± 5.1 0.82
EtCO2 (mmHg) 35.4 ± 2.7 37.2 ± 3.0 40.1 ± 4.5 41.5 ± 4.3 40.6 ± 4.3 43.9 ± 4.2 42 ± 4.1 0.66
pH 7.5 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.4 ± 0.1 7.3 ± 0.1 7.3 ± 0.1 0.87
pO2 (kPa) 24.4 ± 7.6 28.5 ± 5.4 32.1 ± 5.0 29.9 ± 8.6 29.5 ± 7.7 27.1 ± 7.0 28.4 ± 7.0 0.16
pCO2 (kPa) 5.1 ± 0.4 5.5 ± 0.7 5.8 ± 0.7 6.0 ± 0.5 5.9 ± 0.5 6.2 ± 0.7 6.4 ± 0.7 0.56
Lactate (mmol/L) 1.5 ± 0.4 1.9 ± 0.4 2.0 ± 0.4 2.2 ± 0.6 2.2 ± 0.6 2.1 ± 0.7 1.8 ± 0.5 0.04
Hb (g/dL) 81.0 ± 14.0 91.0 ± 12.0 93.0 ± 11.0 94.0 ± 8.0 94.0 ± 9.0 97.0 ± 11.0 94.0 ± 11.0 0.12
SpO2 (%) venous 50.7 ± 11.0 60.1 ± 5.1 51.7 ± 3.6 45.3 ± 6.2 38.3 ± 7.4 38.1 ± 6.0 39.3 ± 5.7 0.21
  1. Respiratory and blood gas analysis parameters measured at the baseline and every hour during experiments in the two groups. Data are reported as mean ± standard deviation
  2. Airways pressure (peak and mean) is reported in cmH2O
  3. Statistically significant difference (p < 0.05) found with multiple comparison between the two groups are reported as a * near the Intervention Group values
  4. ANOVA analysis p values are reported in the dedicated columns next to the Edema group measurements (p values < 0.05 are reported in bold)
  5. pO2 partial pressure of oxygen in arterial blood, pCO2 partial pressure of carbon dioxide in arterial blood, Hb hemoglobin, spO2 oxygen saturated hemoglobin in ven ous blood (jugular vein).