Baseline | 1st hour | 2nd hour | 3rd hour | 4th hour | 5th hour | 6th hour | ANOVA (p value) | |
---|---|---|---|---|---|---|---|---|
Edema group | ||||||||
Airway pressure (peak) | 12.0 ± 3.2 | 15.3 ± 3.4 | 20.8 ± 4.8 | 21.8 ± 4 | 21.8 ± 3.8* | 22.2 ± 3.9 | 23 ± 4.9 | 0.10 |
Airway pressure (mean) | 10.2 ± 4.9 | 13.7 ± 8.7 | 18.2 ± 8.6 | 18.5 ± 8.5 | 18.5 ± 8.5 | 18.7 ± 8.3 | 18.8 ± 8.1 | 0.82 |
EtCO2 (mmHg) | 36.2 ± 2.7 | 37.9 ± 2.6 | 41.1 ± 3.4 | 42.3 ± 2.6 | 40.4 ± 3.4 | 39.4 ± 4.9 | 38.1 ± 5.9 | 0.66 |
pH | 7.5 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 0.87 |
pO2 (kPa) | 35.1 ± 2* | 31.6 ± 8.1 | 33.5 ± 5.5 | 34.6 ± 11.6 | 33.7 ± 9.5 | 29.1 ± 4.8 | 27.2 ± 8.9 | 0.16 |
pCO2 (kPa) | 5.3 ± 0.4 | 5.7 ± 0.4 | 6.2 ± 0.5 | 6.2 ± 0.2 | 6.0 ± 0.2 | 6.0 ± 0.2 | 6.2 ± 0.4 | 0.56 |
Lactate (mmol/L) | 1.8 ± 0.6 | 2.1 ± 0.5 | 2.5 ± 0.5 | 3.2 ± 1.3 | 3.4 ± 1.6 | 3.3 ± 1.6 | 2.6 ± 1.4 | 0.04 |
Hb (gr/dL) | 79.0 ± 7.0 | 84.0 ± 7.0 | 84.0 ± 4.0 | 86.0 ± 6.0 | 89.0 ± 7.0 | 89.0 ± 9.0 | 85.0 ± 10.0 | 0.12 |
SpO2 (%) venous | 59.3 ± 3.6 | 60.1 ± 7.7 | 55.2 ± 11.2 | 51.9 ± 14.7 | 48.5 ± 16.6 | 44.2 ± 15.1 | 44.5 ± 9.0 | 0.21 |
Control group | ||||||||
Airway pressure (peak) | 14.4 ± 3.0 | 17.0 ± 5.0 | 25.0 ± 9.0 | 27.0 ± 4.8 | 26.9 ± 4.1 | 26.9 ± 4.8 | 26.6 ± 4.6 | 0.10 |
Airway pressure (mean) | 9.0 ± 3.6 | 9.9 ± 4.2 | 17.3 ± 5.6 | 18.4 ± 5.2 | 18.7 ± 5.3 | 18.7 ± 4.8 | 18.9 ± 5.1 | 0.82 |
EtCO2 (mmHg) | 35.4 ± 2.7 | 37.2 ± 3.0 | 40.1 ± 4.5 | 41.5 ± 4.3 | 40.6 ± 4.3 | 43.9 ± 4.2 | 42 ± 4.1 | 0.66 |
pH | 7.5 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.3 ± 0.1 | 7.3 ± 0.1 | 0.87 |
pO2 (kPa) | 24.4 ± 7.6 | 28.5 ± 5.4 | 32.1 ± 5.0 | 29.9 ± 8.6 | 29.5 ± 7.7 | 27.1 ± 7.0 | 28.4 ± 7.0 | 0.16 |
pCO2 (kPa) | 5.1 ± 0.4 | 5.5 ± 0.7 | 5.8 ± 0.7 | 6.0 ± 0.5 | 5.9 ± 0.5 | 6.2 ± 0.7 | 6.4 ± 0.7 | 0.56 |
Lactate (mmol/L) | 1.5 ± 0.4 | 1.9 ± 0.4 | 2.0 ± 0.4 | 2.2 ± 0.6 | 2.2 ± 0.6 | 2.1 ± 0.7 | 1.8 ± 0.5 | 0.04 |
Hb (g/dL) | 81.0 ± 14.0 | 91.0 ± 12.0 | 93.0 ± 11.0 | 94.0 ± 8.0 | 94.0 ± 9.0 | 97.0 ± 11.0 | 94.0 ± 11.0 | 0.12 |
SpO2 (%) venous | 50.7 ± 11.0 | 60.1 ± 5.1 | 51.7 ± 3.6 | 45.3 ± 6.2 | 38.3 ± 7.4 | 38.1 ± 6.0 | 39.3 ± 5.7 | 0.21 |