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Table 3 Cytokines concentration, comparison between the two groups, at baseline and at the end of experiment (6th hour)

From: Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model

Cytokine concentration (pg/ml for ascites and blood samples; pg/mg of protein for tissues’ samples)
  Arterial blood Pulm. Art. blood Portal vein blood Hepatic blood Lungs (upper lobe) Lungs (lower lobe) Duodenum Colon Liver Spleen Kidney right Kidney left Ascites
IL6 concentration
Edema group Baseline 1.65
 ± 0.44
1.37
 ± 0.85
1.87
 ± 0.48
1.29
 ± 0.87
// // // // // // // // //
  6th hour 3.99 ± 0.18 4.02 ± 0.15 4.10 ± 0.14 4.05 ± 0.15 * 4.08 ± 0.37 4.09 ± 0.36 3.83 ± 0.26 ** 3.92 ± 0.4 4.31 ± 0.24 3.92 ± 0.4 4.72 ± 0.16 4.67 ± 0.23 3.83 ± 0.6
Control group Baseline 1.31 ± 0.96 1.24 ± 0.97 1.32 ± 0.85 1.73 ± 1.26 // // // // // // // // //
6th hour 3.56 ± 0.59 3.63 ± 0.53 3.62 ± 0.64 3.38 ± 0.65 3.69 ± 0.36 3.46 ± 0.16 3.46 ± 0.16 3.47 ± 0.38 4.30 ± 0.10 3.73 ± 0.3 4.73 ± 0.15 4.96 ± 0.18 4.17 ± 0.06
TNFα concentration
Edema group Baseline 1.95 ± 0.15 1.94 ± 0.13 2.00 ± 0.11 2.00 ± 0.15 // // // // // // // // //
6th hour 3.57 ± 0.16 3.58 ± 0.13 3.61 ± 0.15 3.67 ± 0.18 * 3.57 ± 0.23 3.62 ± 0.24 3.78 ± 0.30 3.54 ± 0.21 4.19 ± 0.22 3.54 ± 0.21 4.41 ± 0.22 4.39 ± 0.21 4.09 ± 0.39
Control group Baseline 1.99
 ± 0.09
1.98
 ± 0.10
2.10
 ± 0.06
2.24
 ± 0.53
// // // // // // // // //
6th hour 3.20 ± 0.58 3.21 ± 0.58 3.15 ± 0.70 2.97 ± 0.74 3.57 ± 0.16 3.91 ± 0.37 3.63 ± 0.05 3.56 ± 0.29 4.34 ± 0.14 3.47 ± 0.22 4.59 ± 0.17 4.60 ± 0.22 4.08 ± 0.16
IL1b concentration
Edema group Baseline 1.02 ± 1.12 0.80 ± 0.10 0.89 ± 1.23 1.00 ± 1.20 // // // // // // // // //
6th hour 2.55 ± 0.33 2.77 ± 0.23 2.75 ± 0.42 2.21 ± 1.12 3.46 ± 0.28 3.41 ± 0.32 3.65 ± 0.47 * 3.37 ± 0.52 4.44 ± 0.22 3.46 ± 0.52 4.69 ± 0.28 4.66 ± 0.27 1.00 ± 1.10
Control group Baseline 1.34 ± 1.01 2.02 ± 1.06 1.39 ± 1.21 1.05 ± 1.05 // // // // // // // // //
6th hour 2.47 ± 0.36 2.10 ± 0.97 1.95 ± 1.18 2.19 ± 1.05 3.39 ± 0.35 3.77 ± 0.28 3.20 ± 0.23 3.15 ± 0.31 4.28 ± 0.18 3.80 ± 0.43 4.57 ± 0.15 4.56 ± 0.09 0.93 ± 1.17
  1. Measure unit: pg/ml for ascites and blood samples and pg/mg of protein for tissues’ samples
  2. Values reported are Log10 of the concentrations (mean ± standard deviation). Statistical differences found with multiple comparison are reported as * (p < 0.05) and ** (p < 0.01), both placed in the Edema group cell (the text is in bold to make the identification of differences between the groups easier)