Table 3 Cytokines concentration, comparison between the two groups, at baseline and at the end of experiment (6th hour)
Cytokine concentration (pg/ml for ascites and blood samples; pg/mg of protein for tissues’ samples) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arterial blood | Pulm. Art. blood | Portal vein blood | Hepatic blood | Lungs (upper lobe) | Lungs (lower lobe) | Duodenum | Colon | Liver | Spleen | Kidney right | Kidney left | Ascites | ||
IL6 concentration | ||||||||||||||
Edema group | Baseline | 1.65 ± 0.44 | 1.37 ± 0.85 | 1.87 ± 0.48 | 1.29 ± 0.87 | // | // | // | // | // | // | // | // | // |
6th hour | 3.99 ± 0.18 | 4.02 ± 0.15 | 4.10 ± 0.14 | 4.05 ± 0.15 * | 4.08 ± 0.37 | 4.09 ± 0.36 | 3.83 ± 0.26 ** | 3.92 ± 0.4 | 4.31 ± 0.24 | 3.92 ± 0.4 | 4.72 ± 0.16 | 4.67 ± 0.23 | 3.83 ± 0.6 | |
Control group | Baseline | 1.31 ± 0.96 | 1.24 ± 0.97 | 1.32 ± 0.85 | 1.73 ± 1.26 | // | // | // | // | // | // | // | // | // |
6th hour | 3.56 ± 0.59 | 3.63 ± 0.53 | 3.62 ± 0.64 | 3.38 ± 0.65 | 3.69 ± 0.36 | 3.46 ± 0.16 | 3.46 ± 0.16 | 3.47 ± 0.38 | 4.30 ± 0.10 | 3.73 ± 0.3 | 4.73 ± 0.15 | 4.96 ± 0.18 | 4.17 ± 0.06 | |
TNFα concentration | ||||||||||||||
Edema group | Baseline | 1.95 ± 0.15 | 1.94 ± 0.13 | 2.00 ± 0.11 | 2.00 ± 0.15 | // | // | // | // | // | // | // | // | // |
6th hour | 3.57 ± 0.16 | 3.58 ± 0.13 | 3.61 ± 0.15 | 3.67 ± 0.18 * | 3.57 ± 0.23 | 3.62 ± 0.24 | 3.78 ± 0.30 | 3.54 ± 0.21 | 4.19 ± 0.22 | 3.54 ± 0.21 | 4.41 ± 0.22 | 4.39 ± 0.21 | 4.09 ± 0.39 | |
Control group | Baseline | 1.99 ± 0.09 | 1.98 ± 0.10 | 2.10 ± 0.06 | 2.24 ± 0.53 | // | // | // | // | // | // | // | // | // |
6th hour | 3.20 ± 0.58 | 3.21 ± 0.58 | 3.15 ± 0.70 | 2.97 ± 0.74 | 3.57 ± 0.16 | 3.91 ± 0.37 | 3.63 ± 0.05 | 3.56 ± 0.29 | 4.34 ± 0.14 | 3.47 ± 0.22 | 4.59 ± 0.17 | 4.60 ± 0.22 | 4.08 ± 0.16 | |
IL1b concentration | ||||||||||||||
Edema group | Baseline | 1.02 ± 1.12 | 0.80 ± 0.10 | 0.89 ± 1.23 | 1.00 ± 1.20 | // | // | // | // | // | // | // | // | // |
6th hour | 2.55 ± 0.33 | 2.77 ± 0.23 | 2.75 ± 0.42 | 2.21 ± 1.12 | 3.46 ± 0.28 | 3.41 ± 0.32 | 3.65 ± 0.47 * | 3.37 ± 0.52 | 4.44 ± 0.22 | 3.46 ± 0.52 | 4.69 ± 0.28 | 4.66 ± 0.27 | 1.00 ± 1.10 | |
Control group | Baseline | 1.34 ± 1.01 | 2.02 ± 1.06 | 1.39 ± 1.21 | 1.05 ± 1.05 | // | // | // | // | // | // | // | // | // |
6th hour | 2.47 ± 0.36 | 2.10 ± 0.97 | 1.95 ± 1.18 | 2.19 ± 1.05 | 3.39 ± 0.35 | 3.77 ± 0.28 | 3.20 ± 0.23 | 3.15 ± 0.31 | 4.28 ± 0.18 | 3.80 ± 0.43 | 4.57 ± 0.15 | 4.56 ± 0.09 | 0.93 ± 1.17 | |