Fig. 5

Glucose consumption and lactate generation during the extracorporeal treatment simulation (n = 10). Glucose is consumed continuously. Likewise, lactate is generated as a product of cell metabolism. Also, there is a difference in concentrations before and after cell filter CC1 until the end of the treatment, showing that the cells are still active. pH values pressures in the plasma before and after cell filter CC1 during the extracorporeal treatment simulation (n = 10). Purified GC have a low pH, especially on day 3. After mixing with the physiologically conditioned plasma pool, the resulting pH is about 7.2 and decreases continuously by the metabolic activity of the cells. Oxygen and carbon dioxide partial pressures in the plasma before and after cell filter CC1 during the extracorporeal treatment simulation (n = 10). Oxygen is consumed, and carbon dioxide is generated as a product of cell metabolism