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Intensive Care Medicine Experimental
Fig. 7 | Intensive Care Medicine Experimental

Fig. 7

From: Induction of severe hypoxemia and low lung recruitability for the evaluation of therapeutic ventilation strategies: a translational model of combined surfactant-depletion and ventilator-induced lung injury

Fig. 7

Computed tomography. Representative computed tomography (CT) images of the basal lungs segments of a pig following lavage-induced surfactant depletion and 3 h of injurious ventilation. Images were taken during ventilation with PEEP of 15 vs. 6 mbar and a VT of 6 mL/kg body weight. Ground glass opacities ( >), interlobar and intralobular septal thickening (→) are representative of the severity of lung injury. Note the significant increase of atelectatic regions (*) as a sign of derecruitment in the dependent lung areas upon PEEP reduction

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