Articles

Volume infusion cooling increases end-tidal carbon dioxide and results in faster and deeper cooling during intra-cardiopulmonary resuscitation hypothermia induction

Intra-arrest hypothermia induction may provide more benefit than inducing hypothermia after return of spontaneous circulation. However, little is understood about the interaction between patient physiology and...

Authors: Joshua W. Lampe, George Bratinov, Theodore R. Weiland III, Uday Illindala, Robert A. Berg and Lance B. Becker

The effects of airway pressure release ventilation on respiratory mechanics in extrapulmonary lung injury

Lung injury is often studied without consideration for pathologic changes in the chest wall. In order to reduce the incidence of lung injury using preemptive mechanical ventilation, it is important to recogniz...

Authors: Michaela Kollisch-Singule, Bryanna Emr, Sumeet V. Jain, Penny Andrews, Joshua Satalin, Jiao Liu, Elizabeth Porcellio, Van Kenyon, Guirong Wang, William Marx, Louis A. Gatto, Gary F. Nieman and Nader M. Habashi

Lung anatomy, energy load, and ventilator-induced lung injury

High tidal volume can cause ventilator-induced lung injury (VILI), but positive end-expiratory pressure (PEEP) is thought to be protective. We aimed to find the volumetric VILI threshold and see whether PEEP i...

Authors: Alessandro Protti, Davide T. Andreis, Marta Milesi, Giacomo E. Iapichino, Massimo Monti, Beatrice Comini, Paola Pugni, Valentina Melis, Alessandro Santini, Daniele Dondossola, Stefano Gatti, Luciano Lombardi, Emiliano Votta, Eleonora Carlesso and Luciano Gattinoni

Computational simulation indicates that moderately high-frequency ventilation can allow safe reduction of tidal volumes and airway pressures in ARDS patients

A recent prospective trial using porcine models of severe acute respiratory distress syndrome (ARDS) indicated that positive-pressure ventilation delivered by a conventional intensive care ventilator at a mode...

Authors: Wenfei Wang, Anup Das, Oanna Cole, Marc Chikhani, Jonathan G. Hardman and Declan G. Bates

Noradrenalin effectively rescues mice from blast lung injury caused by laser-induced shock waves

Blast lung injuries (BLI) caused by blast waves are extremely critical in the prehospital setting, and hypotension is thought to be the main cause of death in such cases. The present study aimed to elucidate t...

Authors: Hiroki Miyawaki, Daizoh Saitoh, Kohsuke Hagisawa, Midori Noguchi, Shunichi Sato, Manabu Kinoshita, Hiromi Miyazaki, Yasushi Satoh, Nahoko Harada and Toshihisa Sakamoto

Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury

Upregulation of the endothelin axis has been observed in pulmonary tissue after brain death, contributing to primary graft dysfunction and ischaemia reperfusion injury. The current study aimed to develop a nov...

Authors: Ryan P. Watts, Izabela Bilska, Sara Diab, Kimble R. Dunster, Andrew C. Bulmer, Adrian G. Barnett and John F. Fraser

Mechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cells

Several mechanisms are associated with brain dysfunction during sepsis; one of the most important are activation of microglia and astrocytes. Activation of glial cells induces changes in permeability of the bl...

Authors: Monique Michels, Amanda V. Steckert, João Quevedo, Tatiana Barichello and Felipe Dal-Pizzol

Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury

The potential for mesenchymal stem cells (MSCs) to reduce the severity of experimental lung injury has been established in several pre-clinical studies. We have recently demonstrated that MSCs, and MSC-secrete...

Authors: Mairead Hayes, Gerard F. Curley, Claire Masterson, James Devaney, Daniel O’Toole and John G. Laffey

Microbiological study of ventilator-associated pneumonia (VAP) after implantation of pneumonia program zero (NZ)

Authors: R Fernández Fernández, MR Ramírez Puerta, ME Yuste Ossorio, O Moreno Romero and M Muñoz Garach

Analysis of the effectiveness of a new system of automatic spray hands in ICU

Authors: J Canovas, A Lopez, D Torres, A Burruezo, L Capilla and A Carrillo

Prediction of major bleeding in cirrhotic ICU patients using the dic score and coagulation parameters

Authors: A Drolz, T Horvatits, K Roedl, K Rutter, N Kneidinger, C Bopp, R Wüstenberg, C Zauner, G Heinz, P Schellongowski, T Perkmann, M Trauner and V Fuhrmann

Assessment of mortality post-ICU associated to the intensive care unit length of stay

Authors: F Gómez Triana, P Carcelén Rodríguez, ZE Aray Delpino, D Monge Donaire, TL Álvarez Pérez, FC Tarancón Maján, SM Cortés Díaz, A Marcos Gutiérrez and AC Caballero Zirena

Outcomes of critical patients with tracheostomy: proposal of a decannulation protocol

Authors: C Duro, C Granja, S Castro, A Cardoso and S Mestre

Impact of proactive nurse participation in ICU family conferences: a mixed-method study

Authors: M Garrouste-Orgeas, A Max, C Grégoire, S Ruckly, M Kloeckner, S Brochon, E Pichot, C Simons, M El Mhadri, C Bruel, F Philippart, J Fournier, K Tiercelet, J-F Timsit and B Misset

Elective ventilation as an improvement measure in organ and tissue donation process

Authors: F Segura, D Daga, A Puerto, J Pérez-Vacas, A Fernández-Porcel and MA Frutos

Brain death and potential organ donors in neurocritical care mortality

Authors: V Spatenkova, O Bradac and P Suchomel

Baseline observation of performance and inter-professional utilisation of institutional hospital electronic technologies to access and communicate key clinical information in a central london teaching hospital critical care unit

Authors: R Chevrier, K Child, S Shah, T Best and P Hopkins

Introduction of weekly multidisciplinary teammeetings in a tertiary cardiothoracic critical care unit: evaluation of staff satisfaction and impact on clinical outcomes

Authors: S Gelvez-Zapata, R D'Oliveiro, K Eriksson, J Bracken, M Pontin and N Jones

A quality improvement comparative audit on theimpact of competency based basic intensive care medicine (ICM) training on the confidence levels of medical senior house officers registrars dealing with intensive care procedures in acutely ill patients

Authors: V Gulia, A Goel, S Kumari, R Kumari and N Arora

Markers of endothelial dysfunction in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs. ringer's acetate

Authors: RB Müller, SR Ostrowski, N Haase, J Wetterslev, A Perner and PI Johansson

Sphingosine-1-phosphate is a novel biomarker in sepsis severity

Authors: A Nierhaus, MS Winkler, M Holzmann, E Mudersbach, A Bauer, L Robbe, C Zahrte, E Schwedhelm, G Daum, S Kluge and C Zoellner

Characteristics associated with low risk of significant coronary stenosis after an episode of acute coronary syndrome

Authors: R Blancas, Ó Martínez González, M Chana, D Ballesteros, B López Matamal, MÁ Alonso and C Martín Parra

Behavioral determinants of hand hygiene compliance in a pediatric intensive care unit from Brazil

Authors: ASC Belela-Anacleto, DM Kusahara, MA Peterlini and M Pedreira

Stability of vancomycin hydrochloride solutions in high concentration and extended time of infusion

Authors: MA Peterlini, APS Barbosa and M Pedreira

Inaccuracies in calculating predicted body weight and its impact on safe ventilator settings

Authors: I OBrien, A Middleditch and C Bigham

Lung protective vs. standard ventilation during laparoscopic surgery in obese patients. preliminary results of a randomized, controlled trial

Authors: DL Grieco, A Russo, MS Vallecoccia, L Polidori, B Costantini, V Simili, F Varone, G Scambia, E Marana and M Antonelli

ECCO₂R, a french national survey

Authors: B Deniau, JD Ricard, J Messika, D Dreyfuss and S Gaudry

Impact of a major cardiovascular surgical procedure on patients' interests for advance care planning

Authors: F Gigon, C Combescure, P Merlani and B Ricou

Targeting the microcirculation in resuscitation of patients with septic shock: fluid is superior to norepinephrine

Authors: J Xu, Y Yang and H Qiu

Radiation overdose: the utility of ct scanning in self poisoning

Authors: G Sondh, S Noble, RI Docking, P Doherty, A Davidson and A Mackay

Feasibility of ultrasound-based identification of correct central venous access using two acoustic windows

Authors: G Zick, G Elke, D Schaedler, T Becher, L Balke and N Weiler

Intravenous oxygen administration in a rat model of hypoxia

Authors: E Damiani, A Donati and M Singer

Neuroprognostication following out of hospital cardiac arrest - a retrospective study of departmental practice

Authors: E Hindle, M Dunn, M Gillies and G Clegg

Effect of a Lung Rest Strategy During Ecmo in a Porcine Acute Lung Injury Model

Authors: J Araos, P Cruces, P Tapia, L Alegria, P García, T Salomon, F Rodriguez, M Amthauer, G Castro, B Erranz, D Soto, P Carreño, T Medina, F Damiani, G Bugedo and A Bruhn

What we say to families of intensive care unit patients - do they understand?

Authors: S Barbosa, A Ilchenko, A Carmo, F Fernandes, S Nascimento and C Granja

Effects of mild therapeutic hypothermia on acute kidney injury after cardiopulmonary resuscitation

Authors: J Hasslacher, F Barbieri, U Harler, G Lehner, S Dunzendorfer and M Joannidis

Modulation of inflammatory response related to severe peritonitis by polymyxin-B haemoperfusion

Authors: R Coudroy, J-C Lecron, DM Payen and R Robert

Circadian rhythm disruption exists in icu patients

Authors: K Kiss, I Földesi, B Köves, V Csernus and Z Molnár

Are extended and continuous infusions of time dependent antibiotics used in the management of sepsis in england today?

Authors: JA Dunning and JC Roberts

Early transfer of cases from emergency(ER) to ICU (≤1 hour) - does it really make a big difference in outcome? an analysis

Authors: A Kar, A Datta and A Ahmed

Inhalatory sedation in postoperative neurovascular surgery patients

Authors: R Badenes, A Belltall, V Chisbert, M De Fez, A Lozano, P Valls, I Fuentes, E Gracia and F Bilotta

Accuracy of a subcutaneous continuous glucose monitor compared with an intravenous continuous glucose monitor in an intensive care unit

Authors: Y Takahashi, T Yatabe, M Munekage, M Sakaguchi, A Nishigaki, M Yokoyama and K Hanazaki

Predictors of outcome and severity in adult filipino patients with febrile neutropenia

Authors: REM Villalobos, MG Yu, RP Berba and MMJ Juan-Bartolome

Evaluation of risk factors for mortality in hematological malignancy patients admitted to intensive care unit

Authors: I Ileri, R Coskun, K Gundogan, M Guven and M Sungur

Six-hour central venous oxygen saturation has no prognostic value in patients with septic shock

Authors: KM Yoo, KS Kim, GJ Suh, WY Kwon, JS Kim, MJ Park, YJ Choi and K Kim

A comparison of global end-diastolic volume (GEDI) and central venous pressure (CVP) as parameter for volumen assessment in patients during major liver resections

Authors: FJ Redondo Calvo, N Bejarano, D Padilla, P Villarejo, V Baladrón, R Villazalo, AS Yuste and P Arenas

Intensive care unit length of stay can be longer due to the low serum vitamin D levels in patients with chronic obstructive pulmonary disease

Authors: Ş Ö Keşkek and O Altınöz

Highly sensitive troponin t (hstnt) profile for outcome prediction after cardiac surgery

Authors: AS Omar, S Sudarsanan, S Hanoura, H Osman, P Sivadasan, Y Shouman, AK Tuli, R Singh and A Al Khulaifi

Are peripherally inserted central catheters in critical ill patients justified?

Authors: O Martínez González, D Ballesteros, C Martín Parra, M Chana, B López Matamala, MA Alonso Fernández, B Estébanez, J Luján and R Blancas

Improving error reporting at the ICU

Authors: EE Rouw and T van Galen