Fig. 6From: Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injuryBiochemical results of markers of cardiac injury in brain dead and control animals over 24Â h. Upper limit refers to the upper limit of the COBAS reference range. a Creatine kinase MB isoenzyme. b Myoglobin. Both cardiac markers indicated myocardial injury and necrosis. As expected from their biological properties, myoglobin increased faster, but it did not reach statistical significance. CK-MB increased later in brain dead animals and was statistically significant at 24Â hBack to article page