Fig. 2

The endothelial bioreactor (EBR) system ameliorated sepsis induced by cecal ligation and puncture (CLP). a Survival was plotted during a 7-day period (n = 22–25 per group). b Serum ALT and AST were quantified at 48 h after CLP (n = 7–9 per group). c Serum Cr and BUN were measured at 48 h after CLP (n = 7–9 per group). d Representative photomicrographs of lung sections stained with hematoxylin and eosin (HE) and examined at ×200 magnification and of kidney sections stained with periodic acid and Schiff’s reagent (PAS) and examined at ×400 magnification. e Histopathologic mean of lung and kidney injury was scored at ×200 magnification at 72 h after CLP (n = 6 per group, at least ten fields were reviewed for each slide). *p < 0.05, **p < 0.01, ***p < 0.001. Data are expressed as mean ± SEM. EBR endothelial bioreactor, CLP cecal ligation and puncture, ALT alanine aminotransferase, AST aspartate aminotransferase, Cr creatinine, BUN blood urea nitrogen