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Intensive Care Medicine Experimental

Table 108 (abstract A336). Effects of HFNC on ventilation pattern

From: ESICM LIVES 2016: part one

 

Facial mask (12 L/min)

HFNC (30 L/min)

HFNC (45 L/min

HFNC (60 L/min)

P-value (ANOVA)

Fitting (AIC) Linear

Fitting (AIC) Non-linear

RR (bpm)

21±5

19±4

17±5*

16±5*

<0.001

204.7

206.9

Vt (mL)

499±371

481±376

487±377

482±368

n.s.

-

-

MV (L/min)

9.5±4.1

7.0±2.5*

7.5±3.2*

7.2±2.1*

<0.01

228.2

225.7

MV corr (L/min)

9.2±4.5

6.8±2.7*

7.2±3.4

6.9±2.4*

<0.01

235.9

234.5

ΔEELV (mL)

baseline

81±228

119±178

212±284*

<0.05

425.2

428.1

PEF (L/min)

40.7±23.9

34.8±21.1*

36.7±21.3

36.6±17.6

<0.05

225.1

226.4

ΔPes (cmH2O)

10.0±4.1

8.0±2.9*

7.7±2.9*

7.2±2.3*

<0.01

203.9

202.8

PTPes (cmH2O*s/min)

228±74

178±55*

152±41*

143±44*

<0.001

235.9

202.3

  1. * p<0.05 vs. facial mask by post-hoc Bonferroni test; no other between-phases post-hoc comparison was significant
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