Variables | No troponin release | Possible troponin release | Definite troponin release | p-value |
---|---|---|---|---|
Inflammation/coagulation factors | ||||
C-reactive protein (mg/L) | 149 (72–255) | 172 (74–256) | 206 (60–303) | 0.54 |
Fever (temperature > 38.5°C) | 51 (13%) | 20 (10%) | 19 (27%) | 0.03 |
Platelet count (10/L) | 182 (105–252) | 147 (74–224) | 135 (70–214) | <0.001 |
Prothrombin time (seconds) | 15 (13–16) | 15 (14–17) | 16 (14–19) | <0.001 |
Supply-demand mismatch factors | ||||
Tachycardia (hours HR>120 beats/min) | 0 (0–1) | 0 (0–0) | 0 (0–3) | 0.16 |
Hypotension (hours MAP<60 mm Hg) | 0 (0–0) | 0 (0–1) | 0 (0–1) | 0.002 |
Shock index (hours HR/SBP > 1) | 0 (0–6.0) | 0 (0–5.0) | 2 (0–11) | 0.03 |
Noradrenalin dose (ng/kg/min) | 89 (48–163) | 98 (63–195) | 138 (63–358) | <0.001 |
Respiratory failure (PaO2/FiO2<200) | 273 (65%) | 141 (69%) | 56 (78%) | 0.03 |
Severe anemia (Hb<5.0mmol/L female, <5.5mmol/L males) | 61 (14%) | 51 (25%) | 16 (22%) | 0.005 |
Extrinsic factors | ||||
Acute kidney injury score* | 125 (29%) | 84 (40%) | 33 (46%) | <0.001 |
Acute stroke, | 8 (2%) | 4 (2%) | 3 (4%) | 0.32 |
Use of cardiotoxic medication | 18 (4%) | 16 (8%) | 8 (11%) | 0.01 |
Acute heart failure | 60 (14%) | 26 (13%) | 10 (14%) | 0.79 |
Acute peri/myocarditis | 3 (1%) | 2 (1%) | 1 (1%) | 0.53 |
Acute myocardial infarction | 0 (0%) | 1 (0%) | 2 (3%) | 0.003 |