Lean critically ill (N = 20) | Overweight/obese critically ill (N = 20) | p valuec | Healthy reference (N = 47) | p valued | |
---|---|---|---|---|---|
Baseline characteristics | |||||
Gender (n, % male) | 13 (65) | 12 (60) | 0.9 | 30 (64) | 1 |
BMI, kg/m2 (mean ± SEM) | 22.4 ± 0.4 | 29.3 ± 0.9 | <0.0001 | 24.8 ± 3.6 | 0.2 |
Age, years (mean ± SEM) | 57.2 ± 3.8 | 56.9 ± 3.4 | 0.4 | 58 ± 2.4 | 0.7 |
APACHE II score (mean ± SEM) | 18.6 ± 6 | 19.3 ± 6.3 | 0.6 | ||
Diagnostic admission category (n) | 2 | 3 | 0.6 | ||
Cardiac surgery | 2 | 1 | |||
Complicated surgerya | 3 | 5 | |||
Multiple trauma or burns | 3 | 3 | |||
Hematologic or oncologic | 4 | 1 | |||
Respiratory | 4 | 6 | |||
Other disease exacerbationsb | 2 | 1 | |||
Other sepsis | |||||
Received steroid therapy (n, %) | 0 (0) | 0 (0) | 1 |