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Intensive Care Medicine Experimental
Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model

Fig. 5

The percent change in both the duration at expiration (T Low ), which is set by changes in lung physiology (see Fig. 2b) and the tidal volume (Vt) over time in both the high (OD + H DS ) and low (OD + L DS ) dynamic strain groups. a TLow is set by changing lung physiology and will require shortening with increasing lung pathology/elastance. This suggests worsening lung injury with time in the OD + HDS group but not in the OD + LDS group. b Shortening TLow, with increasing lung pathology, will necessitate a reduction in Vt over time, which was seen in the OD + HDS group but not in the OD + LDS group. (â—‹, mean of the distribution)

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