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Intensive Care Medicine Experimental
Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Effect of continuous dialysis on blood pH in acidemic hypercapnic animals with severe acute kidney injury: a randomized experimental study comparing high vs. low bicarbonate affluent

Fig. 1

Temporal acid-base variation based on group. Panel a shows the pH changes over time (mixed model: group vs. pH interaction, P = 0.089; timepoint vs. pH interaction, P < 0.001; timepoint vs. group interaction, P = 0.003). Panel b shows the PaCO2 changes over time (mixed model: group vs. PaCO2 interaction, P = 0.913; timepoint vs. PaCO2 interaction, P = 0.311; timepoint vs. group interaction, P = 0.899). Panel c shows the SBE evolution over time (mixed model: group vs. SBE interaction, P = 0.02; timepoint vs. SBE interaction, P < 0.001, timepoint vs. group interaction, P < 0.001). Panel d shows the HCO3 changes over time (mixed model: group vs. HCO3 interaction, P = 0.401; timepoint vs. HCO3, P = 0.607; timepoint vs. group interaction, P = 0.664). SBE denotes standard base excess. Light gray boxplots were not used in analysis. *Wilcoxon post hoc analysis, P < 0.05 vs. baseline. #Mann-Whitney post hoc analysis, variable variation from baseline to 3 h; P < 0.05 vs. group 40. $Mann-Whitney post hoc analysis, P < 0.05 vs. group 40

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