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Table 2 Inoculation dose and bronchoalveolar lavages

From: Protective ventilation reduces Pseudomonas aeruginosa growth in lung tissue in a porcine pneumonia model

Variable

Group

0 h

p

6 h

p

Inoculation dose

Protective (n = 8)

11.0 ± 0.1

 

-

 

(log10cfu)

Control (n = 8)

10.9 ± 0.2

0.05

-

-

P. aeruginosa BAL

Protective (n = 8)

0.0(0.0/0.2)

 

4.0(2.9/4.8)

 

(log10cfu × 100 μL−1)

Control (n = 8)

0.0(0.0/0.0)

N/A

3.8(3.3/4.6)

0.96

TNFα BAL

Protective (n = 8)

1.0(1.0/1.5)

 

3.6(3.1/3.7)

 

(log10ng x L−1)

Control (n = 8)

1.8(1.7/1.9)

<0.05*

3.3(2.8/3.6)

0.37

IL6 BAL

Protective (n = 8)

1.7(1.7/1.7)

 

2.6(1.9/2.9)

 

(log10ng x L−1)

Control (n = 8)

2.6(1.7/2.9)

<0.05*

2.6(2.0/3.0)

0.96

  1. Inoculation dose of Pseudomonas (P.) aeruginosa, colony forming units (cfu), mean ± SD, p-value from general linear model. Growth in BAL (bronchoalveolar lavage), TNFα (tumor necrosis factor alpha) and IL6 (interleukin 6) in BAL, median(lower/upper quartile), p-values from Mann-Whitney U test, * denotes p < 0.05, N/A (not applicable).