Variable | Group | 0 h | 3 h | 6 h |
---|---|---|---|---|
P. aeruginosa lung | PS (n = 2) | - | - | 0.0 ± 0.0 |
(log10cfu x g−1) | CS (n = 2) | - | - | 0.0 ± 0.0 |
P. aeruginosa BAL | PS (n = 2) | 0.0(0.0/0.0) | - | 0.0(0.0/0.0) |
(log10cfu × 100 μL−1) | CS (n = 2) | 0.0(0.0/0.0) | - | 0.0(0.0/0.0) |
TNFα BAL | PS (n = 2) | 1.5(1.5/1.5) | - | 1.6(1.3/1.8) |
(log10ng x L−1) | CS (n = 2) | 1.4(1.0/1.7) | - | 1.4(1.0/1.8) |
IL6 BAL | PS (n = 2) | 1.7(1.7/1.7) | - | 1.7(1.7/1.7) |
(log10ng x L−1) | CS (n = 2) | 1.7(1.7/1.7) | - | 1.7(1.7/1.7) |
TNFα | PS (n = 2) | 2.1 ± 0.1 | 2.2 ± 0.1 | 2.3 ± 0.1 |
(log10ng x L−1) | CS (n = 2) | 2.0 ± 0.5 | 2.2 ± 0.0 | 2.1 ± 0.1 |
IL6 | PS (n = 2) | - | 1.9 ± 0.1 | 2.0 ± 0.2 |
(log10ng x L−1) | CS (n = 2) | 1.6 ± 0.0 | 2.0 ± 0.0 | 1.7 ± 0.3 |
Leukocytes | PS (n = 2) | 17 ± 9 | 20 ± 5 | 19 ± 6 |
(109 x L−1) | CS (n = 2) | 19 ± 8 | 21 ± 7 | 22 ± 7 |
Neutrophils | PS (n = 2) | 10 ± 7 | 11 ± 3 | 9 ± 3 |
(109 x L−1) | CS (n = 2) | 7 ± 0 | 10 ± 0 | 11 ± 0 |
PaO2/FiO2 | PS (n = 2) | 454 ± 5 | 404 ± 2 | 448 ± 21 |
(mmHg) | CS (n = 2) | 429 ± 34 | 366 ± 12 | 360 ± 11 |
Wet-to-dry ratio | PS (n = 2) | - | - | 1.9 ± 0.5 |
CS (n = 2) | - | - | 1.8 ± 0.3 | |
P peak | PS (n = 2) | 18 ± 0 | 19 ± 0 | 19 ± 0 |
(cmH2O) | CS (n = 2) | 15 ± 2 | 16 ± 4 | 17 ± 6 |
P mean | PS (n = 2) | 12 ± 0 | 13 ± 1 | 13 ± 1 |
(cmH2O) | CS (n = 2) | 8 ± 1 | 8 ± 1 | 9 ± 3 |
P plateau | PS (n = 2) | 16 ± 0 | 17 ± 1 | 16 ± 0 |
(cmH2O) | CS (n = 2) | 14 ± 2 | 15 ± 4 | 16 ± 7 |
CI | PS (n = 2) | 2.5 ± 0.1 | 3.7 ± 0.7 | 3.2 ± 1.1 |
(L x min−1 x m−2) | CS (n = 2) | 3.3 ± 0.3 | 3.2 ± 0.5 | 3.6 ± 1.1 |
MAP | PS (n = 2) | 70 ± 1 | 81 ± 6 | 74 ± 14 |
(mmHg) | CS (n = 2) | 84 ± 14 | 86 ± 4 | 81 ± 8 |
MPAP | PS (n = 2) | 18 ± 2 | 21 ± 1 | 21 ± 3 |
(mmHg) | CS (n = 2) | 18 ± 1 | 21 ± 1 | 21 ± 1 |
HR | PS (n = 2) | 112 ± 6 | 103 ± 8 | 102 ± 23 |
(beats x min−1) | CS (n = 2) | 100 ± 21 | 103 ± 10 | 113 ± 8 |
PCWP | PS (n = 2) | 9 ± 1 | 7 ± 0 | 7 ± 1 |
(mmHg) | CS (n = 2) | 8 ± 1 | 9 ± 0 | 8 ± 0 |
Temperature | PS (n = 2) | 39.0 ± 0.2 | 37.8 ± 0.6 | 37.7 ± 1.5 |
(°C) | CS (n = 2) | 39.3 ± 0.5 | 39.8 ± 1.4 | 40.3 ± 1.1 |
Lactate | PS (n = 2) | 2.0 ± 0.4 | 0.9 ± 0.2 | 0.9 ± 0.1 |
(mmol x L−1) | CS (n = 2) | 2.1 ± 0.5 | 1.0 ± 0.1 | 0.9 ± 0.1 |