Fig. 5From: In an endotoxaemic model, antibiotic clearance can be affected by different central venous catheter positions, during renal replacement therapyNoradrenaline dose needed to reach a target mean arterial pressure (MAP) of 75 mmHg, with continuous renal replacement therapy (CRRT) through a central venous dialysis catheter (CVDC) in the external jugular vein (EJV) or the femoral vein (FV). Noradrenalin infusion was in the EJV. The dose needed to reach the target MAP was higher when infusion was close to the CVDC, in the EJV, compared to when it was in separate vessels, in the FVBack to article page