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Table 1 Vital parameters

From: In an endotoxaemic model, antibiotic clearance can be affected by different central venous catheter positions, during renal replacement therapy

Vital parameters

Before

LPS

Before CRRT EJV

Before CRRT FV

After CRRT EJV

After CRRT FV

Mean ± SD median(IQR)

Mean ± SD median(IQR)

Mean ± SD median(IQR)

Mean ± SD median(IQR)

Mean ± SD median(IQR)

Heart rate (bpm)

82 ± 16

148 ± 32

149 ± 31

162 ± 46

163 ± 32

MAP (mmHg)

80 ± 9.6

76 ± 6

77 ± 6

75 ± 9

79 ± 7

CO (ml/min)

2.4 ± 0.7

3.0 ± 0.9

2.8 ± 0.75

3.0 ± 1

2.8 ± 0.8

PAWP (mmHg)

21.5 ± 2.7

32 ± 14

28 ± 11

29 ± 13

34 ± 13

SpO2 (%)

99 (96–100)

99 (97–100)

98 (96–100)

100 (98–100)

96 (93–100)

Temp (°C)

36.8 ± 0.4

37.0 ± 1

37.0 ± 0.8

37.1 ± 0.7

37.1 ± 0.9

etCO2 (kPa)

4.7 ± 0.4

4.8 ± 0.8

5.2 ± 0.5

5.0 ± 0.5

5.1 ± 0.6

pH

7.47 ± 0.04

7.36 ± 0.05

7.36 ± 0.04

7.36 ± 0.05

7.37 ± 0.03

pCO2 (kPa)

5.0 ± 0.3

5.9 ± 0.6

6.0 ± 0.5

5.9 ± 0.5

5.8 ± 0.4

pO2 (kPa)

21 ± 3.5

16.0 ± 7.1

15.3 ± 6.9

13.9 ± 4.1

14.8 ± 6.3

HCO3 (mmol/L)

 

22.7 ± 4.9

24.1 ± 1.5

23.9 ± 1.4

23.7 ± 1.5

ScvO2 (%)

48 ± 7

54 ± 13

55 ± 12

51 ± 15

55 ± 16

P-Hb (g/l)

78 ± 5

94 ± 9

97 ± 8

97 ± 10

96 ± 10

P-Potassium (mmol/L)

3.8 ± 0.2

3.9 ± 0.2

3.8 ± 0.2

3.9 ± 0.2

3.9 ± 0.2

P-Sodium (mmol/L)

136 ± 1.5

135 ± 1.3

135 ± 1.2

135 ± 1.3

135 ± 1.3

P-Calcium (mmol/L)

1.3 ± 0.1

1.4 ± 0.07

1.4 ± 0.07

1.4 ± 0.08

1.4 ± 0.07

P-Chloride (mmol/L)

104 ± 1.6

104 ± 1.2

104 ± 1.4

105 ± 1.5

105 ± 1.4

P-Glucose (mmol/L)

7.7 ± 1.2

7.8 ± 2.1

7.9 ± 2.1

7.3 ± 1.7

7.3 ± 1.7

P-Lactate (mmol/L)

1.6 ± 0.5

2.4 ± 1.2

2.4 ± 1.1

2.4 ± 1.3

2.5 ± 1.1

  1. Vital parameters before LPS-infusion, before after CRRT (continuous renal replacement therapy) in the EJV (external jugular vein) or FV (femoral vein), bpm (beats per minute), MAP (mean arterial pressure), CO (cardiac output), PAWP (pulmonary artery wedge pressure), SpO2 (oxygen saturation), etCO2 (end tidal carbon dioxide), pCO2 (arterial carbon dioxide pressure) pO2 (arterial oxygen pressure), HCO3 (bicarbonate), PA-pO2 (pulmonary artery oxygen pressure) ScvO2 (central venous oxygen saturation), Hb (haemoglobin), P (plasma), p (pressure)