Efficacy of endotracheal tube clamping to prevent positive airways pressure loss and pressure behavior after reconnection: a bench study

Intensive Care Medicine Experimental

Table 2 Alveolar pressure at 5, 15 and 30 s after disconnection from the mechanical ventilator according to type of clamp for ETT ID 7 and 8 mm

ETT	Clamp	Timepoint	Paw			End-expiration vs end-inspiration	End-expiration vs 50%-end-inspiration	End-inspiration vs 50%-end-inspiration
ETT	Clamp	Timepoint	End-expiration	End-inspiration	50%-end-inspiration	p value	p value	p value
7 mm	Klemmer	5 s	8.7 (8,6;8,9)	19 (18,8;19,3)	14.5 (14,3;15)	< 0.001	< 0.001	< 0.001
		15 s	6.6 (6,6;6,7)	16 (15,5;16,1)	12 (11,35;12)	< 0.001	< 0.001	<0.001
		30 s	4.5 (4,5;4,5)	12 (11,2;12,2)	9.5 (9,25;9,75)	< 0.001	< 0.001	0.033
	Chest-Tube	5 s	9 (8,95;9,1)	19.2 (19;19,6)	15 (15;15)	< 0.001	< 0.001	<0.001
		15 s	6.3 (6,25;6,35)	15 (14,5;15,5)	13.4 (12,7;13,7)	< 0.001	< 0.001	0.099
		30 s	4 (3,95;4,15)	10.5 (9,75;10,6)	11.7 (11,4;11,9)	< 0.001	< 0.001	0.078
8 mm	Klemmer	5 s	6.8 (6,75;6,8)	18 (17,5;18,5)	14.5 (13,8; 14,8)	0.001	0.008	0.241
		15 s	2.6 (2,55:2,65)	12 (12;12,4)	11.5 (10,8;11,8)	0.033	0.021	1
		30 s	0 (0;0)	7 (5,9;8)	8.3 (8,15;8,65)	0.017	0.019	0.498
	Chest-Tube	5 s	8 (7,85;8,15)	20 (19;20)	15 (14;15,5)	< 0.001	0.001	0.001
		15 s	6 (5,9;6)	16.8 (15,95;17,4)	13.8 (11,9;13,9)	< 0.001	0.002	0.002
		30 s	4.4 (4,4;4,45)	14 (13;15)	12.8 (10,4;12,9)	< 0.001	0.019	0.004

The data are shown as median with 1st and 3rd quartiles, endotracheal tube; Paw, airway pressure; end-expiration, clamping during end-expiratory occlusion; end-inspiration, clamping during end-inspiratory occlusion; 50%-end-inspiration, clamping during end-inspiratory occlusion with tidal volume halved; Klemmer, Rochester-Pèan forceps; Chest-Tube, tubing clamp forceps 20 cm. p-values are adjusted for take into account multiplicity