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Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill,  invasively mechanically ventilated COVID-19 patients

Fig. 1

Vilobelimab drug concentration. 5 value(s) from vilobelimab patients and 1 value(s) from placebo patients have been excluded from this figure due to incorrect timing or implausible values. Values below the lower limit of quantification are set to zero. Values above the upper limit of quantification are set to the upper limit of quantification. Box plot: lower line of box = 1st quartile, line inside box = median, upper line of box = 3rd quartile, +  = mean, lower/upper whisker = minimum/maximum value below/above lower/upper line of box + 1.5 * (3rd quartile–1st quartile), circle = values below/above whiskers. HD  Hospital discharge; SOC  Standard of care; Vilo  Vilobelimab

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