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Intensive Care Medicine Experimental
Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia

Fig. 2

Changes in systemic hemodynamic in response to bilateral splanchnic denervation or sham procedure during ovine Gram-negative bacteremia. Mean arterial pressure (A), heart rate (B), and core body temperature (C) during infusion of Escherichia coli from 0 to 30-h. Animals were randomized to either splanchnic-denervated (n = 10) or untreated (sham, n = 9) at 24-h of bacteremia. Baseline is the mean of the 20th hour of the baseline period, and times 23 to 30-h of bacteremia are means of 1-h intervals. Data are presented as treatment group-specific mean ± SEM. P values represent the results of a 2-way ANOVA assessing differences between the groups (splanchnic-denervated vs. sham) and treatment time points (from 24 to 30-h of Gram-negative bacteremia) and the interaction between group and time. A two-sided P value < 0.05 was considered to be significant

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