Skip to main content
Intensive Care Medicine Experimental
Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia

Fig. 5

Changes in clinical status in response to bilateral splanchnic denervation or sham during ovine Gram-negative bacteremia. Cumulative food consumption (A), respiration rate (B) and cumulative water consumption (C), during infusion of Escherichia coli from 0 to 30-h. Animals were randomized to either splanchnic-denervated (n = 10) or untreated (sham, n = 9) at 24-h of bacteremia. Baseline is the average of the 20th hour of the baseline period, and times 23 to 30-h of bacteremia are means of 1-h intervals. Data are presented as treatment group-specific mean ± SEM. P values represent the results of a 2-way ANOVA assessing differences between the groups (splanchnic-denervated vs. sham) and treatment time points (from 24 to 30-h of Gram-negative bacteremia) and the interaction between group and time. A two-sided P value < 0.05 was considered to be significant

Back to article page