From: Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients
N = 496 | Complicated outcome in ward | Hazard ratio | p value | |
---|---|---|---|---|
Baseline sTREM-1 cutoff | ||||
< 224 pg/mL | 351 | 83 (23.6%) | 1 | |
≥ 224 pg/mL | 145 | 60 (41.4%) | 1.5 (1.1–2.1) | 0.0216 |
COPD | ||||
No | 464 | 124 (26.7%) | 1 | |
Yes | 32 | 19 (59.4%) | 2.0 (1.2–3.3) | 0.0045 |
Corticosteroids at inclusion | ||||
No | 191 | 31 (16.2%) | 1 | |
Yes | 305 | 112 (36.7%) | 2.3 (1.5–3.4) | < 0.0001 |
N = 247 | Death in ICU | Hazard ratio | p value | |
---|---|---|---|---|
Baseline sTREM-1 cutoff | ||||
< 287 pg/mL | 160 | 10 (6.3%) | 1 | |
≥ 287 pg/mL | 87 | 34 (39.1%) | 3.8 (1.8–8.0) | 0.0003 |
Ischemic cardiopathy | ||||
No | 229 | 34 (14.8%) | 1 | |
Yes | 18 | 10 (55.6%) | 2.9 (1.4–6.1) | 0.004 |
Chronic treatment with Corticosteroids | ||||
No | 230 | 36 (15.7%) | 1 | |
Yes | 17 | 8 (47.1%) | 2.9 (1.3–6.7) | 0.01 |