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Intensive Care Medicine Experimental
Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions

Fig. 1

Dose titration of fecal slurry shows a threshold disease severity effect at site 1. Kaplan–Meier survival curves (A), temperature (B), MSS (C), and percent weight change (D) over time in FIP-treated and sham-treated mice at site 1. See series 1 for experimental details (Table 1). Data are presented as median ± interquartile range for sham-treated mice (n = 8; 4 male, 4 female), 0.5 mg/g fecal slurry (n = 6; 3 male, 3 female), 0.75 mg/g fecal slurry (n = 6; 3 male, 3 female), 1.0 mg/g fecal slurry (n = 6; 3 male, 3 female), 1.5 mg/g fecal slurry (n = 9; 5 male, 4 female), and 2.5 mg/g fecal slurry (n = 6; 3 male, 3 female)

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