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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions

Fig. 2

Dose titration of fecal slurry shows a threshold disease severity effect at site 2. Kaplan–Meier survival curves (A), temperature (B), MSS (C), percent weight change (D), and Hill equation (E) over time in FIP-treated and sham-treated mice at site 2. See series 3 for experimental details (Table 1). Data are presented as median ± interquartile range from sham-treated mice (n = 6; 3 male, 3 female), 0.5 mg/g fecal slurry (n = 8; 4 male, 4 female), 0.625 mg/g fecal slurry (n = 8; 4 male, 4 female), and 0.75 mg/g fecal slurry (n = 8; 4 male, 4 female)

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