Skip to main content
Intensive Care Medicine Experimental
Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions

Fig. 3

Reproducibility of fecal-induced peritonitis model between sites. Kaplan–Meier survival curves (A), temperature (B), MSS (C), and percent weight change (D) over time in FIP-treated and sham-treated mice. Data are presented as median ± interquartile range from FIP mice with 0.75 mg/g at site 1 (n = 20; 10 male and 10 female) and FIP mice with 0.75 mg/g at site 2 (n = 8; 4 male and 4 female); sham animals were pooled between both sites (n = 6; 3 males and 3 females). See series 3 at site 1 and site 2 for experimental details (Table 1). Survival curves between site 1 and site 2 were analyzed using a Log-rank (Mantel–Cox) test; p-values < 0.05 were considered significant

Back to article page