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Intensive Care Medicine Experimental
Fig. 6 | Intensive Care Medicine Experimental

Fig. 6

From: Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions

Fig. 6

Disease severity in FIP model is dependent on fecal slurry batch. Kaplan–Meier survival curves (A), temperature (B), MSS (C), and percent weight change (D) over time in FIP-treated and sham-treated mice. Animals received FIP with 0.75 mg/g; see series 3 (2021) and series 4 (2020) at site 2 for experimental details (Table 1). Data are presented as median ± interquartile range from sham-treated mice (n = 4; 2 male, 2 female), FIP-treated mice with 2020 batch (n = 8; 4 male, 4 female), and FIP-treated mice with 2021 batch (n = 8; 4 male, 4 female)

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