Intensive Care Medicine Experimental

Table 1 Summary results of meta-analysis data on preclinical evidence of MSC efficacy in TBI models. Data extracted from [34]

From: MesenchymAl stromal cells for Traumatic bRain Injury (MATRIx): a study protocol for a multicenter, double-blind, randomised, placebo-controlled phase II trial

	Sensorimotor function	Cognitive function	Anatomical damage
Acute
Number of comparisons	56	20	14
Absolute effect size [95% CI]	1.14 [− 1.41, − 0.88]	0.91 [0.49, 1.33]	0.24 [− 0.04, 0.51]
p value	< 0.0001	< 0.0001	0.092
Chronic
Number of comparisons	29	23	20
Absolute effect size [95% CI]	1.66 [− 2.04, − 1.29]	2.11 [1.56, 2.66]	1.34 [0.89, 1.80]
p value	< 0.0001	< 0.0001	< 0.0001

Back to article page