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Table 1 displays the baseline characteristics of the population and hsTnT serum concentrations in survived and deceased patients

From: Timing and threshold of high sensitive troponin T measurement for the prediction of mortality after cardiac surgery: a retrospective cohort analysis

 

Deceased

Survived

p

Demographics

   

 n

100

2079

 

 Height at admission (cm) (mean (SD))

169.00 (9.48)

170.44 (11.24)

0.206

 Weight at admission (kg) (mean (SD))

78.05 (17.93)

80.95 (19.46)

0.144

 Age at admission (mean (SD))

71.45 (10.08)

66.95 (10.95)

 < 0.001

 Sex = male (%)

38 (38.0)

550 (26.5)

0.015

Procedure

   

 Intervention CABG (n (%))

49 (49.0)

1161 (55.8)

0.214

 Intervention AVR (n (%))

40 (40.0)

726 (34.9)

0.351

 Intervention Valve (non AVR) (n (%))

54 (54.0)

976 (46.9)

0.002

Preexisting conditions

   

 Lung diseasea (n (%))

14 (14.0)

192 (9.2)

0.157

 Diabetes (n (%))

29 (29.0)

421 (20.3)

0.047

 Art. hypertension (n (%))

66 (66.0)

1359 (65.4)

0.982

 Renal dysfunction (n (%))

37 (37.0)

323 (15.5)

 < 0.001

Premedication

   

 Betablocker (n (%))

52 (52.0)

1078 (51.9)

1.000

 ACE inhibitor (n (%))

28 (28.0)

721 (34.7)

0.205

 Statin (n (%))

52 (52.0)

1217 (58.5)

0.234

Outcome

   

 First hs Troponin T d0 (ng/L) (median [IQR])

2,103.00 [1147.00, 5,191.00]

898.00 [538.00, 1,554.00]

 < 0.001

 Second hs Troponin T d1 (ng/L) (median [IQR])

2,012.00 [1049.75, 5,910.00]

590.00 [344.75, 1,092.00]

 < 0.001

 Third hs Troponin T d2 (ng/L) (median [IQR])

1,818.00 [734.00, 5,674.00]

386.00 [233.00, 717.25]

 < 0.001

 Fourth hs Troponin T d3(ng/L) (median [IQR])

1,501.00 [650.50, 3,731.00]

389.00 [219.50, 747.00]

 < 0.001

AKI KDIGO within first 48 h (n (%))

  

 < 0.001

 KDIGO 0

16 (16.0)

40 (1.9)

 

 KDIGO 1

2 (2.0)

296 (14.2)

 

 KDIGO 2

30 (30.0)

1670 (80.3)

 

 KDIGO 3

52 (52.0)

73 (3.5)

 

 Norepinephrine max. dose (µg/kg/min) (mean (SD))

0.38 (0.28)

0.15 (0.13)

 < 0.001

 Days of stay at ICU (mean (SD))

12.86 (15.38)

5.59 (7.18)

 < 0.001

 Lactate avg. at d0 (mmol/L) (mean (SD))

3.67 (2.58)

1.69 (0.73)

 < 0.001

 Lactate avg. at d1 (mmol/L) (mean (SD))

3.24 (3.25)

1.41 (0.50)

 < 0.001

 SAPS3 (mean (SD))

59.12 (15.70)

43.07 (10.30)

 < 0.001

 Cross clamp time (min) (mean (SD))

103.73 (67.66)

72.64 (39.82)

 < 0.001

 CPB time (min) (mean (SD))

211.02 (111.68)

119.81 (59.56)

 < 0.001

  1. Values are presented in mean (SD) or median [IQR] as appropriate due to distribution. Dichotomous variables are counted in n (%). Please note that more than one procedure can have been performed in one patient
  2. AVR aortic valve replacement, CABG coronary artery bypass grafting, AKI acute kidney Injury, KDIGO Kidney Disease: Improving Global Outcomes classes 1–4, CPB Cardio Pulmonary Bypass
  3. aIncludes COPD, bronchial asthma, autoimmune diseases with pulmonary involvement, and pulmonary involvement in oncological diseases