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Intensive Care Medicine Experimental
Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Hemodynamic effects of supplemental oxygen versus air in simulated blood loss in healthy volunteers: a randomized, controlled, double-blind, crossover trial

Fig. 1

Lower body negative pressure (LBNP) model, graphics reused from protocol under CC BY 4.0 license [14]. The subject was positioned inside (1) the LBNP chamber which was (2) sealed just above the level of the iliac crest and connected to (3) a vacuum pump controlled by (4) a pressure control unit. The chamber pressure was displayed on (5) a pressure monitor. Hemodynamic variables including (6) heart rate (HR) from an ECG, (7) mean arterial pressure (MAP) from a finger cuff and (8) stroke volume (SV) from Doppler ultrasound were transmitted to (9) a data acquisition device and (10) sampled on a computer continuously. The treatment was administered on (11) a reservoired face mask. (12, 13) Two cylinders containing oxygen and air were connected to (14) a concealment container from which only one tube continued to the face mask. Whether the tube connected to the oxygen or air cylinder continued to the subject was given by the randomization list

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