Table 1 Patient characteristics

Demographics

Age

61.0 [56.0–69.0]

61.0 [56.0–70.0]

63.0 [58.2–67.5]

0.851

Weight

89.0 [75.0–100.0]

85.0 [73.9–100.0]

90.0 [80.0–109.0]

0.387

Height

175.0 [165.0–181.0]

173.0 [160.0–180.0]

177.5 [170.0–184.8]

0.049

Male

39 (74)

24 (69)

15 (83)

0.409

SOFA Score

14.0 [12.0–16.0]

13.0 [10.5–15.0]

15.0 [14.2–17.8]

0.006

SAPS II

55.0 [40.0–65.0]

50.0 [37.0–63.5]

60.5 [52.0–67.2]

0.126

APACHE II

23.0 [19.0–29.0]

22.0 [16.0–28.0]

26.0 [23.0–28.8]

0.098

Comorbidities

 Ischemic Heart Disease

8 (15)

7 (20)

1 (6)

0.324

 Chronic Heart Failure

7 (13)

2 (6)

5 (28)

0.069

 Peripheral Vascular Disease

3 (6)

2 (6)

1 (6)

1

 Chronic Arterial Hypertension

17 (32)

12 (34)

5 (28)

0.865

 Diabetes mellitus Type 1 or 2

14 (26)

10 (29)

4 (22)

0.867

 Diabetes mellitus with End Organ Damage

1 (2)

1 (3)

0 (0)

1

 Cerebrovascular Disease

5 (9)

3 (9)

2 (11)

1

 Chronic Obstructive Pulmonary Disease

3 (6)

3 (9)

0 (0)

0.515

 Peptic Ulcer Disease

1 (2)

1 (3)

0 (0)

1

 Mild Liver Disease

2 (4)

2 (6)

0 (0)

0.785

 Moderate to Severe Liver Disease

3 (6)

2 (6)

1 (6)

1

 Moderate to Severe Chronic Kidney Disease

8 (15)

6 (17)

2 (11)

0.86

 Solid Tumor (Localized)

5 (9)

4 (11)

1 (6)

0.844

 Solid Tumor (Metastatic)

1 (2)

1 (3)

0 (0)

1

 Leukemia

3 (6)

3 (9)

0 (0)

0.515

 Lymphoma

1 (2)

1 (3)

0 (0)

1

 Immunisupression

4 (8)

3 (9)

1 (6)

1

Organ support and treatment during ICU stay

Organ support

 Vasopressors

53 (100)

35 (100)

18 (100)

1

 HFO/NIV

18 (34)

13 (37)

5 (28)

0.707

 IMV

53 (100)

35 (100)

18 (100)

1

 ECCO2R

3 (6)

2 (6)

1 (6)

1

 ECMO

13 (25)

7 (20)

6 (33)

0.465

 Prone Position

41 (77)

26 (74)

15 (83)

0.69

 iNO

19 (36)

11 (31)

8 (44)

0.527

Drug Therapies

 Corticosteroids

37 (70)

26 (74)

11 (61)

0.501

 Tocilizumab

2 (4)

2 (6)

0 (0)

0.785

 Hydroxychloroquine

11 (21)

7 (20)

4 (22)

1

 Ritonavir/lopinavir

4 (8)

3 (9)

1 (6)

1

 Remdesivir

22 (42)

18 (51)

4 (22)

0.08

 Cytosorb

1 (2)

0 (0)

1 (6)

0.732

 PEX

1 (2)

1 (3)

0 (0)

1

 Baricitinib

1 (2)

1 (3)

0 (0)

1

Outcome parameters

 LOS ICU

24.0 [12.0, 32.0]

23.0 [12.0, 32.0]

29.5 [13.5, 45.2]

0.198

 LOS Hospital

41.0 [28.5, 44.2]

36.0 [26.0, 42.0]

42.0 [40.0, 45.0]

0.53

 Survivor 28 days

20 (40)

12 (36)

8 (47)

0.67

 Survivor 6 months

10 (23)

6 (21)

4 (27)

0.945